(2,8-BIS(TRIFLUOROMETHYL)QUINOLIN-4-YL)(PYRIDIN-2-YL)METHANONE

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Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H8F6N2O
Molecular Weight	370.2486
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of (2,8-BIS(TRIFLUOROMETHYL)QUINOLIN-4-YL)(PYRIDIN-2-YL)METHANONE

Structure Search

SMILES

FC(F)(F)C1=NC2=C(C=CC=C2C(=C1)C(=O)C3=NC=CC=C3)C(F)(F)F

InChI

InChIKey=GZTUXOWPGYDWNO-UHFFFAOYSA-N

InChI=1S/C17H8F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h1-8H

HIDE SMILES / InChI

Molecular Formula	C17H8F6N2O
Molecular Weight	370.2486
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:41:05 GMT 2023` Edited by `admin` on `Sat Dec 16 10:41:05 GMT 2023`
Record UNII	F292WNT81D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

(2,8-BIS(TRIFLUOROMETHYL)QUINOLIN-4-YL)(PYRIDIN-2-YL)METHANONE

Systematic Name

English

MEFLOQUINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]

Common Name

English

MEFLOQUINE HYDROCHLORIDE IMPURITY B [WHO-IP]

Common Name

English

2-PYRIDYL 2,8-BIS(TRIFLUOROMETHYL)-4-QUINOLYL KETONE

Systematic Name

English

METHANONE, (2,8-BIS(TRIFLUOROMETHYL)-4-QUINOLINYL)-2-PYRIDINYL-

Systematic Name

English

Code System Code Type Description

PUBCHEM

9951239

Created by admin on Sat Dec 16 10:41:05 GMT 2023 , Edited by admin on Sat Dec 16 10:41:05 GMT 2023

PRIMARY

ECHA (EC/EINECS)

252-763-6

Created by admin on Sat Dec 16 10:41:05 GMT 2023 , Edited by admin on Sat Dec 16 10:41:05 GMT 2023

PRIMARY

CAS

35853-55-5

Created by admin on Sat Dec 16 10:41:05 GMT 2023 , Edited by admin on Sat Dec 16 10:41:05 GMT 2023

PRIMARY

EPA CompTox

DTXSID00957262

Created by admin on Sat Dec 16 10:41:05 GMT 2023 , Edited by admin on Sat Dec 16 10:41:05 GMT 2023

PRIMARY

FDA UNII

F292WNT81D

Created by admin on Sat Dec 16 10:41:05 GMT 2023 , Edited by admin on Sat Dec 16 10:41:05 GMT 2023

PRIMARY

Related Record Type Details


					5Y9L3636O3

MEFLOQUINE HYDROCHLORIDE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP


					5Y9L3636O3

MEFLOQUINE HYDROCHLORIDE

PARENT -> IMPURITY

Comments:

In the chromatogram obtained with solution (1) the following impurities, if present, are eluted at the following relative retention with reference to mefloquine (retention time about 3.9 minutes):impurity B about 7.4. In the chromatogram obtained with solution (1):the area of any other peak, apart from the principal peak, is not greater than 0.5 times the area of the peak in the chromatogram obtained with solution (2) (0.1%).