U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:48:59 GMT 2023
Edited
by admin
on Sat Dec 16 13:48:59 GMT 2023
Protein Type TRANSPORTER
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
F202H3PMO2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM-DEPENDENT DOPAMINE TRANSPORTER
Common Name English
DAT
Common Name English
DA TRANSPORTER
Common Name English
SLC6A3
Common Name English
SOLUTE CARRIER FAMILY 6 MEMBER 3
Common Name English
DAT1
Common Name English
Code System Code Type Description
CAS
816154-03-7
Created by admin on Sat Dec 16 13:49:02 GMT 2023 , Edited by admin on Sat Dec 16 13:49:02 GMT 2023
PRIMARY
FDA UNII
F202H3PMO2
Created by admin on Sat Dec 16 13:49:02 GMT 2023 , Edited by admin on Sat Dec 16 13:49:02 GMT 2023
PRIMARY
WIKIPEDIA
Dopamine transporter
Created by admin on Sat Dec 16 13:49:02 GMT 2023 , Edited by admin on Sat Dec 16 13:49:02 GMT 2023
PRIMARY
UNIPROT
Q01959
Created by admin on Sat Dec 16 13:49:02 GMT 2023 , Edited by admin on Sat Dec 16 13:49:02 GMT 2023
PRIMARY
From To
1_180 1_189
1_306 2_306
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_181
N 1_188
N 1_205
N 2_181
N 2_188
N 2_205
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TRANSPORTER
INHIBITOR -> TARGET
IC50
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
IN-VITRO
INHIBITOR -> TRANSPORTER
INHIBITOR -> TARGET
BINDING
IC50
INHIBITOR -> TRANSPORTER
INHIBITOR -> TARGET
INHIBITOR -> TARGET
From Rat Membrane Studies
SUBSTRATE -> TRANSPORTER
BINDING
IC50
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Inhibition of [3H]Dopamine(100 uM) uptake in CHO cells expressing human dopamine transporter.
Ki
INHIBITOR -> TARGET
Ki
RADIOLIGAND->TARGET
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
RADIOLIGAND->TARGET
INHIBITOR -> TARGET
INHIBITOR -> TRANSPORTER
INHIBITOR->OFF-TARGET
BINDING
IC50
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
IN-VITRO
RADIOLIGAND->TARGET
Ki
INHIBITOR -> TARGET
RADIOLIGAND->TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
IN-VITRO
IC50
INHIBITOR -> TRANSPORTER
RADIOLIGAND->TARGET
Kd
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Due to a risk of haemolytic anaemia, the U.S. Food and Drug Administration (FDA) withdrew approval for nomifensine on March 20, 1992. Nomifensine was subsequently withdrawn from the Canadian and UK markets as well.
BINDING
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
BINDING
IC50
INHIBITOR -> TRANSPORTER
IN RAT
INHIBITOR -> TARGET
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
RADIOLIGAND->TARGET
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
BINDING
IC50
INHIBITOR -> TRANSPORTER
LIGAND->TRANSPORTER
INHIBITOR -> TARGET
IC50
RADIOLIGAND->TARGET
Binds to cocaine binding site of human dopamine transporter
INHIBITOR -> TARGET
Ki
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL