DISODIUM GUANOSINE TRIPHOSPHATE

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H12N5O14P3.2Na.2H
Molecular Weight	567.1441
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DISODIUM GUANOSINE TRIPHOSPHATE

Structure Search

SMILES

[H+].[H+].[Na+].[Na+].NC1=NC2=C(N=CN2[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1

InChI

InChIKey=FIZIYLKEXVIRHJ-LGVAUZIVSA-L

InChI=1S/C10H16N5O14P3.2Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;/q;2*+1/p-2/t3-,5-,6-,9-;;/m1../s1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H
Molecular Weight	1.0079
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C10H12N5O14P3
Molecular Weight	519.1487
Charge	-4
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
UMP-CMP kinase 5 Target ID: CHEMBL5681 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8573186	Substrate 661
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 5 Target ID: Q9Y3Z3 Gene ID: 25939.0 Gene Symbol: SAMHD1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/23880768	Activator 1430
Ras-like GTPases 5 Target ID: Ras-like GTPases Sources: https://www.ncbi.nlm.nih.gov/pubmed/15236956	Substrate 661

PubMed

Title	Date	PubMed
Phosphoenolpyruvate carboxykinase (guanosine triphosphate) from rat liver cytosol. Separation of homogeneous forms of the enzyme with high and low activity by chromatography on agarose-hexane-guanosine triphosphate.	1978 Dec 12	728402
GTP is the primary activator of the anti-HIV restriction factor SAMHD1.	2013 Aug 30	23880768
GTP and ATP hydrolysis in biology.	2016 Aug	27135900

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:41:48 GMT 2023` Edited by `admin` on `Sat Dec 16 11:41:48 GMT 2023`
Record UNII	F10A90P18X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DISODIUM GUANOSINE TRIPHOSPHATE

Common Name

English

DISODIUM GUANOSINE 5'-TRIPHOSPHATE

Common Name

English

GUANOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), DISODIUM SALT

Systematic Name

English

DISODIUM 5'-GTP

Common Name

English

GTP DISODIUM SALT

Common Name

English

GUANOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), SODIUM SALT (1:2)

Systematic Name

English

Code System Code Type Description

CAS

56001-37-7

Created by admin on Sat Dec 16 11:41:48 GMT 2023 , Edited by admin on Sat Dec 16 11:41:48 GMT 2023

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PUBCHEM

135465086

Created by admin on Sat Dec 16 11:41:48 GMT 2023 , Edited by admin on Sat Dec 16 11:41:48 GMT 2023

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EPA CompTox

DTXSID50971392

Created by admin on Sat Dec 16 11:41:48 GMT 2023 , Edited by admin on Sat Dec 16 11:41:48 GMT 2023

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FDA UNII

F10A90P18X

Created by admin on Sat Dec 16 11:41:48 GMT 2023 , Edited by admin on Sat Dec 16 11:41:48 GMT 2023

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GUANOSINE TRIPHOSPHATE

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