DISODIUM GUANOSINE TRIPHOSPHATE

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H12N5O14P3.2Na.2H
Molecular Weight	567.1441
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DISODIUM GUANOSINE TRIPHOSPHATE

Structure Search

SMILES

[H+].[H+].[Na+].[Na+].NC1=NC2=C(N=CN2[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1

InChI

InChIKey=FIZIYLKEXVIRHJ-LGVAUZIVSA-L

InChI=1S/C10H16N5O14P3.2Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;/q;2*+1/p-2/t3-,5-,6-,9-;;/m1../s1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.98976928
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C10H14N5O14P3
Molecular Weight	521.1645
Charge	-2
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
UMP-CMP kinase 5 Target ID: CHEMBL5681 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8573186	Substrate 661
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 5 Target ID: Q9Y3Z3 Gene ID: 25939.0 Gene Symbol: SAMHD1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/23880768	Activator 1447
Ras-like GTPases 5 Target ID: Ras-like GTPases Sources: https://www.ncbi.nlm.nih.gov/pubmed/15236956	Substrate 661

PubMed

Title	Date	PubMed
GTP and ATP hydrolysis in biology.	2016-08	27135900
GTP is the primary activator of the anti-HIV restriction factor SAMHD1.	2013-08-30	23880768
Phosphoenolpyruvate carboxykinase (guanosine triphosphate) from rat liver cytosol. Separation of homogeneous forms of the enzyme with high and low activity by chromatography on agarose-hexane-guanosine triphosphate.	1978-12-12	728402
[Mechanism of the activating action of guanosine triphosphate (GTP) on the fat oxidazing enzyme system. IV].	1959-02-15	13639918
[Guanosine triphosphate activation of enzyme systems of fatty acid oxidation. III].	1959-01-15	13619678

Substance Class	Chemical Created by `admin` on `Tue Apr 01 16:48:31 GMT 2025` Edited by `admin` on `Tue Apr 01 16:48:31 GMT 2025`
Record UNII	F10A90P18X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DISODIUM GUANOSINE TRIPHOSPHATE

Common Name

English

DISODIUM 5'-GTP

Preferred Name

English

DISODIUM GUANOSINE 5'-TRIPHOSPHATE

Common Name

English

GUANOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), DISODIUM SALT

Systematic Name

English

GTP DISODIUM SALT

Common Name

English

GUANOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), SODIUM SALT (1:2)

Systematic Name

English

Code System Code Type Description

CAS

56001-37-7

Created by admin on Tue Apr 01 16:48:31 GMT 2025 , Edited by admin on Tue Apr 01 16:48:31 GMT 2025

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PUBCHEM

135465086

Created by admin on Tue Apr 01 16:48:31 GMT 2025 , Edited by admin on Tue Apr 01 16:48:31 GMT 2025

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EPA CompTox

DTXSID50971392

Created by admin on Tue Apr 01 16:48:31 GMT 2025 , Edited by admin on Tue Apr 01 16:48:31 GMT 2025

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FDA UNII

F10A90P18X

Created by admin on Tue Apr 01 16:48:31 GMT 2025 , Edited by admin on Tue Apr 01 16:48:31 GMT 2025

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GUANOSINE TRIPHOSPHATE

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