Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 13:21:43 GMT 2023
by
admin
on
Sat Dec 16 13:21:43 GMT 2023
|
| Protein Sub Type | |
| Sequence Type | COMPLETE |
| Record UNII |
F05Y5QQX44
|
| Record Status |
Validated (UNII)
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| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
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Common Name | English | ||
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Code | English | ||
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Code | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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F05Y5QQX44
Created by
admin on Sat Dec 16 13:21:44 GMT 2023 , Edited by admin on Sat Dec 16 13:21:44 GMT 2023
|
PRIMARY | |||
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P10747
Created by
admin on Sat Dec 16 13:21:44 GMT 2023 , Edited by admin on Sat Dec 16 13:21:44 GMT 2023
|
PRIMARY |
| From | To |
|---|---|
| 1_22 | 1_94 |
| 1_48 | 1_68 |
| Glycosylation Type | HUMAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_19 |
| N | 1_53 |
| N | 1_74 |
| N | 1_87 |
| N | 1_111 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
AGONIST -> TARGET |
Superagonist LED TO CYTOKINE STORM
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ACTIVATOR -> TARGET |
GI101 has high binding affinity to CTLA4 acting as a decoy ligand, thereby enhancing the interaction between endogenous CD80 and CD28, leading to the activation of T cells
IN-VIVO
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AGONIST -> TARGET |
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INHIBITOR -> TARGET | |||
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ACTIVATOR -> TARGET |
T cell activation can also be achieved by agonistic stimulation with the CD3 antibody binding to the TCR complex and can be enhanced by costimulation with CD28 antibody.
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DERIVATIVE -> PARENT |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|