Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H16 |
| Molecular Weight | 256.341 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=C2C=CC3=C(C=CC=C3)C2=C(C)C4=CC=CC=C14
InChI
InChIKey=ARSRBNBHOADGJU-UHFFFAOYSA-N
InChI=1S/C20H16/c1-13-16-8-5-6-9-17(16)14(2)20-18(13)12-11-15-7-3-4-10-19(15)20/h3-12H,1-2H3
| Molecular Formula | C20H16 |
| Molecular Weight | 256.341 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation. | 2002-04 |
|
| Deregulated expression of the PCPH proto-oncogene in rat mammary tumors induced with 7,12-dimethylbenz[a]anthracene. | 2002-04 |
|
| Sulfatides and arylsulfatase A activity in major salivary glands of hamster (Mesocricetus auratus) after adenocarcinoma induction in oral cavity. | 2002-04 |
|
| Effect of calorie restriction on mortality kinetics in inbred strains of mice following 7,12-dimethylbenz[a]anthracene treatment. | 2002-04 |
|
| Chemotherapeutic evaluation of 4-hydroxybenzylretinone (4-HBR), a nonhydrolyzable C-linked analog of N-(4-hydroxyphenyl) retinamide (4-HPR) against mammary carcinogenesis. | 2002-03-26 |
|
| Relative importance of maternal and embryonic microsomal epoxide hydrolase in 7,12-dimethylbenz[a]anthracene-induced developmental toxicity. | 2002-03-15 |
|
| Magnetic field exposure increases cell proliferation but does not affect melatonin levels in the mammary gland of female Sprague Dawley rats. | 2002-03-01 |
|
| Altered cytokeratin expression during chemoprevention of experimental hamster buccal pouch carcinogenesis by garlic. | 2002-03 |
|
| Adrenalectomy abrogates reduction of 12-O-tetradecanoylphorbol-13-acetate-induced extracellular signal-regulated protein kinase activity in the epidermis of dietary energy-restricted SENCAR mice: implications of glucocorticoid hormone. | 2002-03 |
|
| Dose-response effects of the COX-2 inhibitor, celecoxib, on the chemoprevention of mammary carcinogenesis. | 2002-02-19 |
|
| Changes in expression of onco- and suppressor genes in peripheral leukocytes--as potential biomarkers of chemical carcinogenesis. | 2002-02-19 |
|
| Some new methodological aspects of the hen's egg test for micronucleus induction (HET-MN). | 2002-02-15 |
|
| Comparison of the chemopreventive potentials of melatonin and vitamin E plus selenium on 7,12-dimethylbenz[a]anthracene-induced inhibition of mouse liver antioxidant enzymes. | 2002-02 |
|
| The mRNA expression of inducible nitric oxide synthase in DMBA-induced hamster buccal-pouch carcinomas using reverse transcription-polymerase chain reaction. | 2002-02 |
|
| Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis. | 2002-02 |
|
| Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol. | 2002-02 |
|
| The mRNA expression of placental glutathione S-transferase isoenzyme in hamster buccal-pouch carcinomas using reverse transcription-polymerase chain reaction. | 2002-02 |
|
| Studies on cancer chemoprevention by traditional folk medicines XXIV. Inhibitory effect of a coumarin derivative, 7-isopentenyloxycoumarin, against tumor-promotion. | 2002-02 |
|
| A correlative study on antimutagenic and chemopreventive activity of Acacia auriculiformis A. Cunn. and Acacia nilotica (L.) Willd. Ex Del. | 2002-02 |
|
| Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation. | 2002-02 |
|
| Chronic exposure to a GSM-like signal (mobile phone) does not stimulate the development of DMBA-induced mammary tumors in rats: results of three consecutive studies. | 2002-02 |
|
| Tibolone and 5alpha-dihydrotestosterone alone or in combination with an antiandrogen in a rat breast tumour model. | 2002-02 |
|
| Interleukin-1alpha up-regulation in vivo by a potent carcinogen 7,12-dimethylbenz(a)anthracene (DMBA) and control of DMBA-induced inflammatory responses. | 2002-01-15 |
|
| Further evaluation of an in vivo micronucleus test on rat and mouse skin: results with five skin carcinogens. | 2002-01-15 |
|
| Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer. | 2002-01 |
|
| Environmental carcinogens and p53 tumor-suppressor gene interactions in a transgenic mouse model for mammary carcinogenesis. | 2002 |
|
| Combined effects of lutenizing hormone-releasing hormone analogue with antiestrogen on rat mammary tumors. | 2001-12-19 |
|
| Decreased focal adhesion kinase suppresses papilloma formation during experimental mouse skin carcinogenesis. | 2001-12-01 |
|
| Anti-tumor-promoting activity of the diterpene from Excoecaria agallocha. II. | 2001-12 |
|
| Chemoprevention of mammary, cervix and nervous system carcinogenesis in animals using cultured Panax ginseng drugs and preliminary clinical trials in patients with precancerous lesions of the esophagus and endometrium. | 2001-12 |
|
| Soy and whey proteins downregulate DMBA-induced liver and mammary gland CYP1 expression in female rats. | 2001-12 |
|
| Chemopreventive efficacy of lycopene on 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. | 2001-12 |
|
| Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. | 2001-12 |
|
| Cancer chemopreventive activity of phenylpropanoid esters of sucrose, vanicoside B and lapathoside A, from Polygonum lapathifolium. | 2001-11-28 |
|
| Induction of melanoma in murine macrophage inflammatory protein 2 transgenic mice heterozygous for inhibitor of kinase/alternate reading frame. | 2001-11-15 |
|
| Cancer chemopreventive activity of odorine and odorinol from Aglaia odorata. | 2001-11 |
|
| Lack of promotion of 7,12-dimethylbenz[a]anthracene-initiated mouse skin carcinogenesis by 1.5 GHz electromagnetic near fields. | 2001-11 |
|
| Cancer chemopreventive agents, serratane-type triterpenoids from Picea jezoensis. | 2001-10-30 |
|
| Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models. | 2001-10-15 |
|
| Activity profile of glutathione-dependent enzymes and respiratory chain complexes in rats supplemented with antioxidants and treated with carcinogens. | 2001-10-15 |
|
| Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of moxifloxacin, a quinolone antibiotic. | 2001-10 |
|
| Chemomodulation of carcinogen metabolising enzymes, antioxidant profiles and skin and forestomach papillomagenesis by Spirulina platensis. | 2001-10 |
|
| New TNF-alpha releasing inhibitors, geraniin and corilagin, in leaves of Acer nikoense, Megusurino-ki. | 2001-10 |
|
| Lack of effect of 94 GHz radio frequency radiation exposure in an animal model of skin carcinogenesis. | 2001-10 |
|
| Antioxidative and antitumor promoting effects of [6]-paradol and its homologs. | 2001-09-20 |
|
| 7,12-Dimethylbenz[a]anthracene inhibition of steroid production in MA-10 mouse Leydig tumor cells is not directly linked to induction of CYP1B1. | 2001-09-15 |
|
| Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis. | 2001-09-06 |
|
| Chemoprevention of DMBA-induced mammary cancer in rats by dietary soy. | 2001-09 |
|
| Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. | 2001 |
|
| S-allylcysteine, a garlic constituent, inhibits 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. | 2001 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:07:19 GMT 2025
by
admin
on
Mon Mar 31 21:07:19 GMT 2025
|
| Record UNII |
F05B6S0395
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
254496
Created by
admin on Mon Mar 31 21:07:19 GMT 2025 , Edited by admin on Mon Mar 31 21:07:19 GMT 2025
|
PRIMARY | |||
|
m4527
Created by
admin on Mon Mar 31 21:07:19 GMT 2025 , Edited by admin on Mon Mar 31 21:07:19 GMT 2025
|
PRIMARY | Merck Index | ||
|
F05B6S0395
Created by
admin on Mon Mar 31 21:07:19 GMT 2025 , Edited by admin on Mon Mar 31 21:07:19 GMT 2025
|
PRIMARY | |||
|
7,12-DIMETHYLBENZ(A)ANTHRACENE
Created by
admin on Mon Mar 31 21:07:19 GMT 2025 , Edited by admin on Mon Mar 31 21:07:19 GMT 2025
|
PRIMARY | |||
|
408823
Created by
admin on Mon Mar 31 21:07:19 GMT 2025 , Edited by admin on Mon Mar 31 21:07:19 GMT 2025
|
PRIMARY | |||
|
DTXSID1020510
Created by
admin on Mon Mar 31 21:07:19 GMT 2025 , Edited by admin on Mon Mar 31 21:07:19 GMT 2025
|
PRIMARY | |||
|
200-359-5
Created by
admin on Mon Mar 31 21:07:19 GMT 2025 , Edited by admin on Mon Mar 31 21:07:19 GMT 2025
|
PRIMARY | |||
|
57-97-6
Created by
admin on Mon Mar 31 21:07:19 GMT 2025 , Edited by admin on Mon Mar 31 21:07:19 GMT 2025
|
PRIMARY | |||
|
2938
Created by
admin on Mon Mar 31 21:07:19 GMT 2025 , Edited by admin on Mon Mar 31 21:07:19 GMT 2025
|
PRIMARY | |||
|
6001
Created by
admin on Mon Mar 31 21:07:19 GMT 2025 , Edited by admin on Mon Mar 31 21:07:19 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
METABOLITE -> PARENT |
in rainbow trout
|
