U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:56:33 GMT 2023
Edited
by admin
on Sat Dec 16 14:56:33 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
EWR59AZK8G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM CHANNEL PROTEIN TYPE 2 SUBUNIT ALPHA
Common Name English
SODIUM CHANNEL PROTEIN BRAIN II SUBUNIT ALPHA
Common Name English
SODIUM CHANNEL PROTEIN TYPE II SUBUNIT ALPHA
Common Name English
HBSC II
Common Name English
NAC2
Common Name English
SCN2A2
Common Name English
VOLTAGE-GATED SODIUM CHANNEL SUBUNIT ALPHA NAV1.2
Common Name English
SCN2A1
Common Name English
Code System Code Type Description
FDA UNII
EWR59AZK8G
Created by admin on Sat Dec 16 14:56:34 GMT 2023 , Edited by admin on Sat Dec 16 14:56:34 GMT 2023
PRIMARY
UNIPROT
Q99250
Created by admin on Sat Dec 16 14:56:34 GMT 2023 , Edited by admin on Sat Dec 16 14:56:34 GMT 2023
PRIMARY
PHAROS
Q99250
Created by admin on Sat Dec 16 14:56:34 GMT 2023 , Edited by admin on Sat Dec 16 14:56:34 GMT 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_212
N 1_285
N 1_291
N 1_297
N 1_303
N 1_308
N 1_340
N 1_1368
N 1_1382
N 1_1393
Related Record Type Details
INHIBITOR -> TARGET
Binds preferentially to Na+ channels in their inactivated state. A high-affinity, stimulus-dependent blocker at the local anesthetic receptor site.
ALLOSTERIC
IC50
INHIBITOR -> TARGET
EC50
INHIBITOR -> TARGET
Binds to inactivated state and prevents activation
INHIBITOR -> TARGET
MAY ALSO BLOCK OTHER SODIUM CHANNELS
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL