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Details

Stereochemistry ACHIRAL
Molecular Formula C16H15N3O2.ClH
Molecular Weight 317.77
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LY-456236

SMILES

Cl.COC1=CC=C(NC2=C3C=C(OC)C=CC3=NC=N2)C=C1

InChI

InChIKey=AVKFOWUSTVWZQN-UHFFFAOYSA-N
InChI=1S/C16H15N3O2.ClH/c1-20-12-5-3-11(4-6-12)19-16-14-9-13(21-2)7-8-15(14)17-10-18-16;/h3-10H,1-2H3,(H,17,18,19);1H

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C16H15N3O2
Molecular Weight 281.3092
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Q13255|||Q9NU10
Gene ID: 2911.0
Gene Symbol: GRM1
Target Organism: Homo sapiens (Human)
140.0 nM [IC50]
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:37:51 GMT 2023
Edited
by admin
on Sat Dec 16 08:37:51 GMT 2023
Record UNII
EU75F68HWQ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LY-456236
Code English
4-QUINAZOLINAMINE, 6-METHOXY-N-(4-METHOXYPHENYL)-, HYDROCHLORIDE (1:1)
Systematic Name English
LY456236 HYDROCHLORIDE
Common Name English
MPMQ
Common Name English
4-QUINAZOLINAMINE, 6-METHOXY-N-(4-METHOXYPHENYL)-, MONOHYDROCHLORIDE
Systematic Name English
6-METHOXY-N-(4-METHOXYPHENYL)QUINAZOLIN-4-AMINE HYDROCHLORIDE
Systematic Name English
Code System Code Type Description
CAS
338736-46-2
Created by admin on Sat Dec 16 08:37:51 GMT 2023 , Edited by admin on Sat Dec 16 08:37:51 GMT 2023
PRIMARY
FDA UNII
EU75F68HWQ
Created by admin on Sat Dec 16 08:37:51 GMT 2023 , Edited by admin on Sat Dec 16 08:37:51 GMT 2023
PRIMARY
PUBCHEM
9926998
Created by admin on Sat Dec 16 08:37:51 GMT 2023 , Edited by admin on Sat Dec 16 08:37:51 GMT 2023
PRIMARY
CAS
670275-75-9
Created by admin on Sat Dec 16 08:37:51 GMT 2023 , Edited by admin on Sat Dec 16 08:37:51 GMT 2023
SUPERSEDED
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