TYROSINE 3-MONOOXYGENASE

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 19:04:08 GMT 2025` Edited by `admin` on `Tue Apr 01 19:04:08 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	EPW0V0G4N1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TH

Preferred Name

English

TYROSINE 3-MONOOXYGENASE

Common Name

English

TYH

Common Name

English

TYROSINE 3-HYDROXYLASE

Common Name

English

Code System Code Type Description

UNIPROT

P07101

Created by admin on Tue Apr 01 19:04:08 GMT 2025 , Edited by admin on Tue Apr 01 19:04:08 GMT 2025

PRIMARY

FDA UNII

EPW0V0G4N1

Created by admin on Tue Apr 01 19:04:08 GMT 2025 , Edited by admin on Tue Apr 01 19:04:08 GMT 2025

PRIMARY

CAS

9036-22-0

Created by admin on Tue Apr 01 19:04:08 GMT 2025 , Edited by admin on Tue Apr 01 19:04:08 GMT 2025

PRIMARY

Related Record Type Details


					X88TTO174Z

RACEMETYROSINE

INHIBITOR -> TARGET

Comments:

Inhibition of tyrosine hydroxylase, the rate-limiting step for catecholamine synthesis in the CNS using oral metyrosine (?-methyltyrosine or AMPT), has been reported to reduce VCFS-related psychosis.

Amount:

Structural Modifications

Modification Type	Location Site	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_18]	DEXFOSFOSERINE	VI4F0K069V
AMINO ACID SUBSTITUTION	[1_70]	DEXFOSFOSERINE	VI4F0K069V
AMINO ACID SUBSTITUTION	[1_61] [1_501]	DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL