Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H16N2.C4H4O4 |
| Molecular Weight | 304.341 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)\C=C\C(O)=O.CN(C)CCC1=CNC2=CC=CC=C12
InChI
InChIKey=OHMVTPSXVQQKPA-WLHGVMLRSA-N
InChI=1S/C12H16N2.C4H4O4/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12;5-3(6)1-2-4(7)8/h3-6,9,13H,7-8H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
| Molecular Formula | C4H4O4 |
| Molecular Weight | 116.0722 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Optical Activity | NONE |
| Molecular Formula | C12H16N2 |
| Molecular Weight | 188.2688 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| A proposed mechanism for the visions of dream sleep. | 1988 Jun |
|
| Dose-response study of N,N-dimethyltryptamine in humans. I. Neuroendocrine, autonomic, and cardiovascular effects. | 1994 Feb |
|
| [Antimycobacterial indole derivatives]. | 1994 Feb |
|
| Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamine and [3H]alniditan. | 1996 Dec |
|
| Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. | 1996 Jan |
|
| Psychedelic effects of ketamine in healthy volunteers: relationship to steady-state plasma concentrations. | 1998 Jan |
|
| Serotonergic and dopaminergic influence of the duration of embryogenesis and intracapsular locomotion of Lymnaea stagnalis L. | 2004 |
|
| Potentially hallucinogenic 5-hydroxytryptamine receptor ligands bufotenine and dimethyltryptamine in blood and tissues. | 2005 |
|
| Endogenous psychoactive tryptamines reconsidered: an anxiolytic role for dimethyltryptamine. | 2005 |
|
| Fast and slow metabolizers of Hoasca. | 2005 Jun |
|
| Psychological effects of (S)-ketamine and N,N-dimethyltryptamine (DMT): a double-blind, cross-over study in healthy volunteers. | 2005 Nov |
|
| A fatal intoxication following the ingestion of 5-methoxy-N,N-dimethyltryptamine in an ayahuasca preparation. | 2005 Nov-Dec |
|
| Urinary excretion of dietary contaminants in horses. | 2006 Aug |
|
| The mysterious trace amines: protean neuromodulators of synaptic transmission in mammalian brain. | 2006 Aug |
|
| Detection and determination of abused hallucinogens in biological material. | 2006 Dec |
|
| Pharmacologic analysis of non-synonymous coding h5-HT2A SNPs reveals alterations in atypical antipsychotic and agonist efficacies. | 2006 Jan-Feb |
|
| Increased frontal and paralimbic activation following ayahuasca, the pan-Amazonian inebriant. | 2006 May |
|
| Not imagining it. Research into hallucinogens cautiously resumes. | 2006 Nov |
|
| DMT at fifty. | 2007 Dec |
|
| Risk assessment of ritual use of oral dimethyltryptamine (DMT) and harmala alkaloids. | 2007 Jan |
|
| Effects of ayahuasca on psychometric measures of anxiety, panic-like and hopelessness in Santo Daime members. | 2007 Jul 25 |
|
| Further studies on the binding of N1-substituted tryptamines at h5-HT6 receptors. | 2007 Mar 15 |
|
| Prepulse inhibition of the startle reflex and its attentional modulation in the human S-ketamine and N,N-dimethyltryptamine (DMT) models of psychosis. | 2007 May |
|
| The globalization of ayahuasca: harm reduction or benefit maximization? | 2008 Aug |
|
| Secondary metabolites from three Florida sponges with antidepressant activity. | 2008 Feb |
|
| A general approach to the screening and confirmation of tryptamines and phenethylamines by mass spectral fragmentation. | 2008 Jan 15 |
|
| Mismatch negativity generation in the human 5HT2A agonist and NMDA antagonist model of psychosis. | 2008 Jul |
|
| The "vine of the soul" vs. the Controlled Substances Act: implications of the hoasca case. | 2008 Jun |
|
| [Inhibition of return in schizophrenia: a review]. | 2008 Jun |
|
| [Hallucinogen-induced psychological disorders]. | 2008 Jun |
|
| Indolealkylamines: biotransformations and potential drug-drug interactions. | 2008 Jun |
|
| Ayahuasca versus violence--a case report. | 2008 May |
|
| N,N-Dimethyltryptamine and dichloromethane: rearrangement of quaternary ammonium salt product during GC-EI and CI-MS-MS analysis. | 2008 May 12 |
|
| Pharmacological modulation of the neural basis underlying inhibition of return (IOR) in the human 5-HT2A agonist and NMDA antagonist model of psychosis. | 2008 Nov |
|
| Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors. | 2008 Nov |
|
| Identification of N,N-dimethyltryptamine and beta-carbolines in psychotropic ayahuasca beverage. | 2008 Oct |
|
| [Studies on constituents of rootsanel leaves from Desmodium blandum and their cytotoxic activity against growth of several tumor cells]. | 2008 Sep |
|
| Reassessing the cultural and psychopharmacological significance of Banisteriopsis caapi: preparation, classification and use among the Piaroa of Southern Venezuela. | 2008 Sep |
|
| A multi-component LC-MS/MS method for detection of ten plant-derived psychoactive substances in urine. | 2009 Apr 15 |
|
| Optimization of separation and online sample concentration of N,N-dimethyltryptamine and related compounds using MEKC. | 2009 Feb |
|
| Analysis of toxic alkaloids in body samples. | 2009 Mar 10 |
|
| Gas chromatographic analysis of dimethyltryptamine and beta-carboline alkaloids in ayahuasca, an Amazonian psychoactive plant beverage. | 2009 Mar-Apr |
|
| The neural correlates of religious and nonreligious belief. | 2009 Oct 1 |
|
| The chemical basis of pharmacology. | 2010 Dec 7 |
|
| Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts. | 2010 Jan 22 |
|
| Characterization of the synthesis of N,N-dimethyltryptamine by reductive amination using gas chromatography ion trap mass spectrometry. | 2010 Jul |
|
| Alkaloids from Fissistigma latifolium (Dunal) Merr. | 2010 Jun 24 |
|
| Association between Serotonin-Related Polymorphisms in 5HT2A, TPH1, TPH2 Genes and Bipolar Disorder in Korean Population. | 2010 Mar |
|
| Neuronal correlates of visual and auditory alertness in the DMT and ketamine model of psychosis. | 2010 Oct |
|
| Dimethyltryptamine (DMT): subjective effects and patterns of use among Australian recreational users. | 2010 Sep 1 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sun Dec 18 00:14:36 UTC 2022
by
admin
on
Sun Dec 18 00:14:36 UTC 2022
|
| Record UNII |
EP5189LWFM
|
| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID0048896
Created by
admin on Sun Dec 18 00:14:36 UTC 2022 , Edited by admin on Sun Dec 18 00:14:36 UTC 2022
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EP5189LWFM
Created by
admin on Sun Dec 18 00:14:36 UTC 2022 , Edited by admin on Sun Dec 18 00:14:36 UTC 2022
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68677-26-9
Created by
admin on Sun Dec 18 00:14:36 UTC 2022 , Edited by admin on Sun Dec 18 00:14:36 UTC 2022
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60196335
Created by
admin on Sun Dec 18 00:14:36 UTC 2022 , Edited by admin on Sun Dec 18 00:14:36 UTC 2022
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PRIMARY |
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |