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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 15:08:45 GMT 2025
Edited
by admin
on Wed Apr 02 15:08:45 GMT 2025
Protein Type FC FUSION PROTEIN
Protein Sub Type BAFF ANTAGONIST
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
EN2U82XV65
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Povetacicept
INN   USAN  
Official Name English
ALPN-303
Preferred Name English
POVETACICEPT [USAN]
Common Name English
human TACI (transmembrane activator and CAML interactor, tumor necrosis factor receptor superfamily member 13B, TNFRSF13B, CD267) receptor domain 68-110 fragment (K77>E10, F78>Y11, Y102>D35)-mutant (1-43), fused via a GSG4S peptide linker (44-50) with 23
Common Name English
povetacicept [INN]
Common Name English
ALPN-303 (DUAL BAFF/APRIL Fc Fusion Antagonist)
Common Name English
68-110-Tumor necrosis factor receptor superfamily protein TNFRSF13B [77-glutamic acid,78-tyrosine,102-aspartic acid] (human) fusion with peptide linker (GSGGGGS) fusion with immunoglobulin G1 [5-serine,19-alanine,20-glutamic acid,22-alanine,de-C-terminal
Common Name English
Code System Code Type Description
INN
12264
Created by admin on Wed Apr 02 15:08:45 GMT 2025 , Edited by admin on Wed Apr 02 15:08:45 GMT 2025
PRIMARY
USAN
LM-215
Created by admin on Wed Apr 02 15:08:45 GMT 2025 , Edited by admin on Wed Apr 02 15:08:45 GMT 2025
PRIMARY
CAS
2490217-42-8
Created by admin on Wed Apr 02 15:08:45 GMT 2025 , Edited by admin on Wed Apr 02 15:08:45 GMT 2025
PRIMARY
NCI_THESAURUS
C190436
Created by admin on Wed Apr 02 15:08:45 GMT 2025 , Edited by admin on Wed Apr 02 15:08:45 GMT 2025
PRIMARY
FDA UNII
EN2U82XV65
Created by admin on Wed Apr 02 15:08:45 GMT 2025 , Edited by admin on Wed Apr 02 15:08:45 GMT 2025
PRIMARY
SMS_ID
300000047292
Created by admin on Wed Apr 02 15:08:45 GMT 2025 , Edited by admin on Wed Apr 02 15:08:45 GMT 2025
PRIMARY
From To
1_202 1_260
1_96 1_156
2_202 2_260
2_96 2_156
1_64 2_64
1_26 1_37
1_22 1_33
1_61 2_61
2_26 2_37
2_22 2_33
2_4 2_19
1_4 1_19
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_132
N 2_132
Related Record Type Details
TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B MEMBRANE FORM
TARGET -> INHIBITOR
TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13
TARGET -> INHIBITOR
Related Record Type Details
Povetacicept
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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