TISOCROMIDE

COC1=CC2=C(C=C1OC)S(=O)(=O)OC(C2)C(=O)NC(C)CC(C)(C)N(C)C

InChIKey=CXGGLKVQGDLNGH-UHFFFAOYSA-N

InChI=1S/C19H30N2O6S/c1-12(11-19(2,3)21(4)5)20-18(22)16-9-13-8-14(25-6)15(26-7)10-17(13)28(23,24)27-16/h8,10,12,16H,9,11H2,1-7H3,(H,20,22)

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Tisocromide exerts antihypoxic and antidepressant action. The details regarding mechanism of action and use are not available.

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
[Tisocromid, a psychopharmaceutical with antidepressive action].	1979	262371
[Comparison of the cardiotoxic effects of tisocromide and imipramine in animal experiment (proceedings)].	1979 May-Jun	515130
[The clinical effect of a selected sultone (tisocromide) (proceedings)].	1979 May-Jun	390554
[Operational evaluation studies in psychopharmacological research (presented with an example of a comparison between clomipramine and tisocromide)].	1980 Feb	7394083
[Antihypoxic effect of tisochromide (16-244) in comparison with piracetam].	1983 Apr	6867087
Characterization of the antihypoxic activity of tisochromid.	1985	4062921

Patents

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:43:27 GMT 2023` Edited by `admin` on `Fri Dec 15 15:43:27 GMT 2023`
Record UNII	ELK0X0H412
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

TISOCROMIDE

Official Name

English

N-(3-(DIMETHYLAMINO)-1,3-DIMETHYLBUTYL)-6,7-DIMETHOXY-2,1-BENZOXATHIAN-3-CARBOXAMIDE 1,1-DIOXIDE

Systematic Name

English

2,1-BENZOXATHIIN-3-CARBOXAMIDE, N-(3-(DIMETHYLAMINO)-1,3-DIMETHYLBUTYL)-3,4-DIHYDRO-6,7-DIMETHOXY-, 1,1-DIOXIDE

Systematic Name

English

tisocromide [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C26170