ORDESEKIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:00:26 UTC 2023` Edited by `admin` on `Sat Dec 16 15:00:26 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	EJ48MR05C3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ORDESEKIMAB

Official Name

English

HUMAN IGG1 ANTI-IL-15 MONOCLONAL ANTIBODY

Common Name

English

ORDESEKIMAB [USAN]

Common Name

English

MAB146B7

Code

English

AMG-714

Common Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS IL15 (INTERLEUKIN 15, IL-15)), HOMO SAPIENS MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN HOMO SAPIENS (1-448) (VH (HOMO SAPIENS IGHV5-51*01 (95.9%)-(IGHD)-IGHJ4*01 (100%)) CDR-IMGT (8.8.11) (26-33.51-58.97-107) (1-1

Common Name

English

HUMAX-IL 15

Common Name

English

AMG 714 [WHO-DD]

Common Name

English

PRV-015

Code

English

ordesekimab [INN]

Common Name

English

AMG714

Code

English

HUMAX IL15

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN INTERLEUKIN 15) (HUMAN MONOCLONAL AMG 714 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL AMG 714 .KAPPA.-CHAIN, DIMER

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

574517

Created by admin on Sat Dec 16 15:00:26 UTC 2023 , Edited by admin on Sat Dec 16 15:00:26 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C126841

Created by admin on Sat Dec 16 15:00:26 UTC 2023 , Edited by admin on Sat Dec 16 15:00:26 UTC 2023

PRIMARY

CAS

879293-15-9

Created by admin on Sat Dec 16 15:00:26 UTC 2023 , Edited by admin on Sat Dec 16 15:00:26 UTC 2023

NO STRUCTURE GIVEN

INN

11557

Created by admin on Sat Dec 16 15:00:26 UTC 2023 , Edited by admin on Sat Dec 16 15:00:26 UTC 2023

PRIMARY

INN

FDA UNII

EJ48MR05C3

Created by admin on Sat Dec 16 15:00:26 UTC 2023 , Edited by admin on Sat Dec 16 15:00:26 UTC 2023

PRIMARY

ChEMBL

CHEMBL2109467

Created by admin on Sat Dec 16 15:00:26 UTC 2023 , Edited by admin on Sat Dec 16 15:00:26 UTC 2023

PRIMARY

CAS

2394931-19-0

Created by admin on Sat Dec 16 15:00:26 UTC 2023 , Edited by admin on Sat Dec 16 15:00:26 UTC 2023

PRIMARY

USAN

KL-05

Created by admin on Sat Dec 16 15:00:26 UTC 2023 , Edited by admin on Sat Dec 16 15:00:26 UTC 2023

PRIMARY

From	To
1_22	1_96
4_23	4_89
1_145	1_201
1_221	3_214
1_227	2_227
1_230	2_230
1_262	1_322
1_368	1_426
2_22	2_96
2_145	2_201
2_221	4_214
2_262	2_322
2_368	2_426
3_134	3_194
3_23	3_89
4_134	4_194

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					HRJ300HC9W

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					EJ48MR05C3

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL