.ALPHA.-PELTATIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H20O8
Molecular Weight	400.3787
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12COC(=O)[C@]1([H])[C@H](C3=CC(OC)=C(O)C(OC)=C3)C4=CC5=C(OCO5)C(O)=C4C2

InChI

InChIKey=JGGWNGRBXJWAOC-HKJPBSJPSA-N

InChI=1S/C21H20O8/c1-25-13-4-9(5-14(26-2)19(13)23)16-11-6-15-20(29-8-28-15)18(22)12(11)3-10-7-27-21(24)17(10)16/h4-6,10,16-17,22-23H,3,7-8H2,1-2H3/t10-,16+,17-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C21H20O8
Molecular Weight	400.3787
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13233861

α-peltatin is a lignan, which was isolated from different species of Linum and has been studied in patients with advanced neoplasms.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Advanced neoplasms 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13233861	Primary		Not Provided 504	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Effect of podophyllotoxin, alpha-peltatin and beta-peltatin on the cytochrome oxidase activity of sarcoma 37.	1952 Oct	12991048
Response of patients with advanced neoplasms to the intravenous administration of alpha-peltatin.	1954 Jun	13233861

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Intravenous

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:34:12 GMT 2023` Edited by `admin` on `Sat Dec 16 09:34:12 GMT 2023`
Record UNII	EHO76Y1JAO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

.ALPHA.-PELTATIN

Common Name

English

NSC-35463

Code

English

(5R,5AR,8AR)-5,8,8A,9-TETRAHYDRO-10-HYDROXY-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)FURO(3,4:6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE

Systematic Name

English

.ALPHA.-PELTATIN A

Common Name

English

NCI-1074

Code

English

NSC-24817

Code

English

.ALPHA.-PELTATIN [MI]

Common Name

English

FURO(3',4':6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE, 5,8,8A,9-TETRAHYDRO-10-HYDROXY-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-, (5R,5AR,8AR)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

92129