U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry UNKNOWN
Molecular Formula C12H16F3NS
Molecular Weight 263.322
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TIFLOREX

SMILES

CCNC(C)CC1=CC=CC(SC(F)(F)F)=C1

InChI

InChIKey=HNONSDNCRNUTCT-UHFFFAOYSA-N
InChI=1S/C12H16F3NS/c1-3-16-9(2)7-10-5-4-6-11(8-10)17-12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C12H16F3NS
Molecular Weight 263.322
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Tiflorex (also known as (+)-Flutiorex) is a phenylalkylamine derivative patented by Synthelabo S. A. as an anorectic agent. Tiflorex acts as a central nervous system stimulant form amphetamine class with little effect on pulse rate, sleep, or mood. In preclinical models, Tiflorex provoked a dose-dependent reduction in the consumption of the protein-rich diet and a reduction in the consumption of the protein-poor diet.

Approval Year

PubMed

PubMed

TitleDatePubMed
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Dec 16 16:44:51 GMT 2023
Edited
by admin
on Sat Dec 16 16:44:51 GMT 2023
Record UNII
EG3B69DFQ5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TIFLOREX
INN  
INN  
Official Name English
tiflorex [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29728
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID90866374
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
MESH
C012982
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
INN
3845
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
EVMPD
SUB11041MIG
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
SMS_ID
100000082671
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
PUBCHEM
173669
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
CAS
53993-67-2
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
WIKIPEDIA
TIFLOREX
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105447
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
NCI_THESAURUS
C75117
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
FDA UNII
EG3B69DFQ5
Created by admin on Sat Dec 16 16:44:51 GMT 2023 , Edited by admin on Sat Dec 16 16:44:51 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY