DIPYROCETYL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H10O6
Molecular Weight	238.1935
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)OC1=C(OC(C)=O)C(=CC=C1)C(O)=O

InChI

InChIKey=NYIZXMGNIUSNKL-UHFFFAOYSA-N

InChI=1S/C11H10O6/c1-6(12)16-9-5-3-4-8(11(14)15)10(9)17-7(2)13/h3-5H,1-2H3,(H,14,15)

HIDE SMILES / InChI

Molecular Formula	C11H10O6
Molecular Weight	238.1935
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.whocc.no/atc_ddd_index/?code=N02BA09 | https://www.ncbi.nlm.nih.gov/pubmed/15123232

Dipyrocetyl (2,3-diacetyloxybenzoic acid) is a drug used as an analgesics and antipyretics. Besides, was shown, that it may be useful in the treatment of acute lung injury (ALI) associated with acute respiratory distress syndrome (ARDS). Dipyrocetyl possesses the anticoagulation properties, which may contribute directly to improve tissue integrity as well as indirectly by the prevention of activation of pro-inﬂammatory cytokines. In addition, was made a suggestion, that the drug may function as an MMP inhibitor.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
72 kDa type IV collagenase 5 Target ID: P08253 Gene ID: 4313.0 Gene Symbol: MMP2 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/15123232	Inhibitor 8504

Conditions

Condition	Modality	Highest Phase	Product
Pain 619 Sources: https://www.whocc.no/atc_ddd_index/?code=N02BA09	Primary	Not Provided 511	DIPYROCETYL Approved Use Unknown
Fever 23 Sources: https://www.whocc.no/atc_ddd_index/?code=N02BA09	Primary	Not Provided 511	DIPYROCETYL Approved Use Unknown
Acute lung injury associated with acute respiratory distress syndrome 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15123232	Primary	Not Provided 511	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Effective attenuation of endotoxin-induced acute lung injury by 2,3-diacetyloxybenzoic acid in two independent animal models.	2004	15123232

Patents

Sample Use Guides

In Vivo Use Guide

3 g

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:11:46 GMT 2025` Edited by `admin` on `Mon Mar 31 18:11:46 GMT 2025`
Record UNII	EF5UVE254C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DIPYROCETYL [MI]

Preferred Name

English

DIPYROCETYL

Official Name

English

Dipyrocetyl [WHO-DD]

Common Name

English

2,3-DIHYDROXYBENZOIC ACID DIACETATE

Systematic Name

English

NSC-758212

Code

English

dipyrocetyl [INN]

Common Name

English

DIACETYLSALICYLIC ACID

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

N02BA79