DIPYROCETYL

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H10O6
Molecular Weight	238.1935
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DIPYROCETYL

Structure Search

SMILES

CC(=O)OC1=CC=CC(C(O)=O)=C1OC(C)=O

InChI

InChIKey=NYIZXMGNIUSNKL-UHFFFAOYSA-N

InChI=1S/C11H10O6/c1-6(12)16-9-5-3-4-8(11(14)15)10(9)17-7(2)13/h3-5H,1-2H3,(H,14,15)

HIDE SMILES / InChI

Molecular Formula	C11H10O6
Molecular Weight	238.1935
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.whocc.no/atc_ddd_index/?code=N02BA09 | https://www.ncbi.nlm.nih.gov/pubmed/15123232

Dipyrocetyl (2,3-diacetyloxybenzoic acid) is a drug used as an analgesics and antipyretics. Besides, was shown, that it may be useful in the treatment of acute lung injury (ALI) associated with acute respiratory distress syndrome (ARDS). Dipyrocetyl possesses the anticoagulation properties, which may contribute directly to improve tissue integrity as well as indirectly by the prevention of activation of pro-inﬂammatory cytokines. In addition, was made a suggestion, that the drug may function as an MMP inhibitor.

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
72 kDa type IV collagenase 5 Target ID: P08253 Gene ID: 4313.0 Gene Symbol: MMP2 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/15123232	Inhibitor 8297

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pain 614 Sources: https://www.whocc.no/atc_ddd_index/?code=N02BA09	Primary		Not Provided 504	DIPYROCETYL Approved Use Unknown
Fever 23 Sources: https://www.whocc.no/atc_ddd_index/?code=N02BA09	Primary		Not Provided 504	DIPYROCETYL Approved Use Unknown
Acute lung injury associated with acute respiratory distress syndrome 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15123232	Primary		Not Provided 504	Unknown Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed

Patents

Patents

Sample Use Guides

In Vivo Use Guide

3 g

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:52:34 GMT 2023` Edited by `admin` on `Fri Dec 15 15:52:34 GMT 2023`
Record UNII	EF5UVE254C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DIPYROCETYL

Official Name

English

DIPYROCETYL [MI]

Common Name

English

Dipyrocetyl [WHO-DD]

Common Name

English

2,3-DIHYDROXYBENZOIC ACID DIACETATE

Systematic Name

English

NSC-758212

Code

English

dipyrocetyl [INN]

Common Name

English

DIACETYLSALICYLIC ACID

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

N02BA79

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

WHO-ATC

N02BA09

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

WHO-VATC

QN02BA79

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

NCI_THESAURUS

C257

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

WHO-VATC

QM01BA02

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

WHO-VATC

QN02BA09

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

WHO-ATC

M01BA02

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

WHO-VATC

QN02BA59

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

WHO-ATC

N02BA59

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

Code System Code Type Description

DRUG BANK

DB13839

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

PRIMARY

EVMPD

SUB07231MIG

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

PRIMARY

CAS

486-79-3

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

PRIMARY

ChEMBL

CHEMBL1451173

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

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FDA UNII

EF5UVE254C

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

PRIMARY

SMS_ID

100000082356

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

PRIMARY

NCI_THESAURUS

C80542

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

PRIMARY

ECHA (EC/EINECS)

207-641-7

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

PRIMARY

INN

645

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

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DRUG CENTRAL

3160

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

PRIMARY

MERCK INDEX

m1122

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

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Merck Index

NSC

758212

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

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PUBCHEM

68093

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

PRIMARY

EPA CompTox

DTXSID9045976

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

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WIKIPEDIA

Dipyrocetyl

Created by admin on Fri Dec 15 15:52:34 GMT 2023 , Edited by admin on Fri Dec 15 15:52:34 GMT 2023

PRIMARY

Related Record Type Details


					EF5UVE254C

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