| Stereochemistry | ACHIRAL |
| Molecular Formula | C3H2N2 |
| Molecular Weight | 66.0614 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
N#CCC#N
InChI
InChIKey=CUONGYYJJVDODC-UHFFFAOYSA-N
InChI=1S/C3H2N2/c4-2-1-3-5/h1H2
| Molecular Formula | C3H2N2 |
| Molecular Weight | 66.0614 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Malononitrile is a weak cyanocarbon acid with exceptional reactivity. It is used extensively as a reactant or reaction intermediate since the methylene group and either one or both cyano groups can take part in condensation reactions to give a variety of additional products and heterocyclic compounds. This unique reactivity makes malononitrile an important chemical in research and in medical, industrial, and agricultural chemistry. In the late 1940's malononitrile was used experimentally in the treatment of schizophrenia and depression.
Approval Year
PubMed
Patents
Sample Use Guides
In the late 1940's malononitrile was used experimentally in the treatment of schizophrenia and depression. ... Patients were given an intravenous infusion of 5% malononitrile for 10-69 min. The total dose during each treatment ranged from 1 to 6 mg/kg. Treatments were given 2-3 times/wk, with at least 1 day intervals. Ten to 20 min after the beginning of the infusion, all patients experienced tachycardia. In addition, redness, nausea, vomiting, headache, shivering, muscle spasms, & numbness were reported with varying frequency.
Route of Administration:
Intravenous