U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 18:30:33 GMT 2023
Edited
by admin
on Sat Dec 16 18:30:33 GMT 2023
Protein Type NUCLEOLAR PROTEIN
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
EA6MNS8JXJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NUCLEOLIN
Common Name English
PROTEIN C23
Common Name English
Code System Code Type Description
UNIPROT
P19338
Created by admin on Sat Dec 16 18:30:33 GMT 2023 , Edited by admin on Sat Dec 16 18:30:33 GMT 2023
PRIMARY
FDA UNII
EA6MNS8JXJ
Created by admin on Sat Dec 16 18:30:33 GMT 2023 , Edited by admin on Sat Dec 16 18:30:33 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template, a critical interaction for rRNA biogenesis that is overexpressed in cancer cells.
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL