Imapextide

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 17:18:44 GMT 2025` Edited by `admin` on `Wed Apr 02 17:18:44 GMT 2025`
Protein Type	FUSION PROTEINS
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	E8L272T7FX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Imapextide

Official Name

English

9-29-Glucagon-like peptide I [9-[N-(17-carboxy-1-oxoheptadecyl)-L-aspartic acid],16-glutamic acid,19-valine,20-arginine,28-arginine] (human) fusion protein with 30-39-exendin-4 (human)

Preferred Name

English

glucagon-like peptide 1(15-35) [human GLP-1(15-35)] (1-21 in the real sequence), [G22>E8, A25>V11, K26>R12, K34>R20]-variant, fused to the C-terminal (30-39)-peptide

Common Name

English

N-(17-carboxyheptadecanoyl)-L-?-aspartyl-L-valyl-L-seryl-L-seryl-Ltyrosyl-L-leucyl-L-?-glutamyl-L-?-glutamyl-L-glutaminyl-L-alanyl-Lvalyl-L-arginyl-L-?-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-Ltryptophyl-L-leucyl-L-valyl-L-arginylglycylglycyl-L-prol

Common Name

English

imapextide [INN]

Common Name

English

Code System Code Type Description

INN

13532

Created by admin on Wed Apr 02 17:18:44 GMT 2025 , Edited by admin on Wed Apr 02 17:18:44 GMT 2025

PRIMARY

FDA UNII

E8L272T7FX

Created by admin on Wed Apr 02 17:18:44 GMT 2025 , Edited by admin on Wed Apr 02 17:18:44 GMT 2025

PRIMARY

CAS

3004569-93-8

Created by admin on Wed Apr 02 17:18:44 GMT 2025 , Edited by admin on Wed Apr 02 17:18:44 GMT 2025

PRIMARY

Related Record Type Details


					E6329K2XFW

Imapextide sodium

SALT/SOLVATE -> PARENT

Amount:


					EF38T7N5MI

GLUCAGON-LIKE PEPTIDE 1 RECEPTOR

TARGET -> INHIBITOR

Interaction Type:

PRECLINICAL

Amount:

Related Record Type Details


					E8L272T7FX

Imapextide

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS	D		1,16-Dicarboxyhexadecaneaspartamide	4J7XH73P9G

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL