U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:45:36 GMT 2023
Edited
by admin
on Sat Dec 16 15:45:36 GMT 2023
Protein Type REGULATOR PROTEIN
Protein Sub Type INITIATION-FACTOR
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
E7D5919XXG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRANSLATION INITIATION FACTOR EIF-2B
Common Name English
EIF2B
Common Name English
EIF-2B
Common Name English
Code System Code Type Description
FDA UNII
E7D5919XXG
Created by admin on Sat Dec 16 15:45:36 GMT 2023 , Edited by admin on Sat Dec 16 15:45:36 GMT 2023
PRIMARY
Related Record Type Details
ACTIVATOR -> TARGET
DNL343 is a selective, orally bioavailable, central nervous system (CNS)–penetrant activator of eukaryotic translation initiation factor 2B (eIF2B).
PRECLINICAL
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL