Falbikitug

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:38:36 GMT 2023` Edited by `admin` on `Sat Dec 16 14:38:36 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	E4JL3K3CI6
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Falbikitug

Official Name

English

AZD-0171

Code

English

gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV3-15*07 (86.9%)--(IGHD) -IGHJ1*01(90.9%), CDR-IMGT [8.10.9] (26-33.51-60.99-107))(1-118) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1K120, CH3 D12, L14 (CH1 K120 (215) (119-216),hinge 1-15 (217-231

Common Name

English

falbikitug [INN]

Common Name

English

Immunoglobulin G1, anti-(human leukemia inhibitory factor) (human-Wistar rat monoclonal AZD0171 γ1-chain), disulfide with human-Wistar monoclonal AZD0171 κ-chain, dimer

Common Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens LIF (LIF interleukin 6 family cytokine, leukemia inhibitory factor)], humanized monoclonal antibody

Common Name

English

AZD0171

Code

English

Code System Code Type Description

CAS

2740565-02-8

Created by admin on Sat Dec 16 14:38:36 GMT 2023 , Edited by admin on Sat Dec 16 14:38:36 GMT 2023

PRIMARY

FDA UNII

E4JL3K3CI6

Created by admin on Sat Dec 16 14:38:36 GMT 2023 , Edited by admin on Sat Dec 16 14:38:36 GMT 2023

PRIMARY

INN

12512

Created by admin on Sat Dec 16 14:38:36 GMT 2023 , Edited by admin on Sat Dec 16 14:38:36 GMT 2023

PRIMARY

NCI_THESAURUS

C156176

Created by admin on Sat Dec 16 14:38:36 GMT 2023 , Edited by admin on Sat Dec 16 14:38:36 GMT 2023

PRIMARY

From	To
1_22	1_98
2_22	2_98
1_145	1_201
2_145	2_201
1_262	1_322
2_262	2_322
3_23	3_93
4_23	4_93
3_140	3_200
4_140	4_200
1_221	3_220
2_221	4_220
1_368	1_426
2_368	2_426
1_227	2_227
1_230	2_230

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					9LN7HV55R1

LEUKEMIA INHIBITORY FACTOR

TARGET -> INHIBITOR

Interaction Type:

BINDING

Amount:

Related Record Type Details


					E4JL3K3CI6

Falbikitug

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL