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Details

Stereochemistry ACHIRAL
Molecular Formula C14H16BNO
Molecular Weight 225.094
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-AMINOETHOXYDIPHENYLBORATE

SMILES

NCCOB(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=BLZVCIGGICSWIG-UHFFFAOYSA-N
InChI=1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2

HIDE SMILES / InChI

Molecular Formula C14H16BNO
Molecular Weight 225.094
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Calcium-sensing receptor stimulation induces nonselective cation channel activation in breast cancer cells.
2006
Increased store-operated and 1-oleoyl-2-acetyl-sn-glycerol-induced calcium influx in monocytes is mediated by transient receptor potential canonical channels in human essential hypertension.
2007 Apr
2-Aminoethoxydiphenylborane is an acute inhibitor of directly photosensitive retinal ganglion cell activity in vitro and in vivo.
2007 Apr 11
Third activity of Bordetella adenylate cyclase (AC) toxin-hemolysin. Membrane translocation of AC domain polypeptide promotes calcium influx into CD11b+ monocytes independently of the catalytic and hemolytic activities.
2007 Feb 2
2-Aminoethyl diphenylborinate analogues: selective inhibition for store-operated Ca2+ entry.
2007 Jan 12
Role of TRPV1 and intracellular Ca2+ in excitation of cardiac sensory neurons by bradykinin.
2007 Jul
Metabotropic glutamate receptors in the lateral superior olive activate TRP-like channels: age- and experience-dependent regulation.
2007 May
Activation properties of heterologously expressed mammalian TRPV2: evidence for species dependence.
2007 May 25
Non-genomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor.
2007 May 29
Human malarial parasite, Plasmodium falciparum, displays capacitative calcium entry: 2-aminoethyl diphenylborinate blocks the signal transduction pathway of melatonin action on the P. falciparum cell cycle.
2007 Nov
Pharmacological characterization and molecular determinants of the activation of transient receptor potential V2 channel orthologs by 2-aminoethoxydiphenyl borate.
2007 Nov
Monocytes from spontaneously hypertensive rats show increased store-operated and second messenger-operated calcium influx mediated by transient receptor potential canonical Type 3 channels.
2007 Oct
Ca2+-dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides.
2007 Oct 15
A nitric oxide/Ca(2+)/calmodulin/ERK1/2 mitogen-activated protein kinase pathway is involved in the mitogenic effect of IL-1beta in human astrocytoma cells.
2008 Apr
Oxygen-regulated protein-150 prevents calcium homeostasis deregulation and apoptosis induced by oxidized LDL in vascular cells.
2008 Aug
Activation of the aryl hydrocarbon receptor by the calcium/calmodulin-dependent protein kinase kinase inhibitor 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid (STO-609).
2008 Dec
Initial and extended inflammatory messages of the nongenomic signaling pathway of the TCDD-activated Ah receptor in U937 macrophages.
2008 Dec 15
Inhibition of transient receptor potential canonical channels impairs cytokinesis in human malignant gliomas.
2008 Feb
Low concentrations of sphingosylphosphorylcholine enhance pulmonary artery vasoreactivity: the role of protein kinase C delta and Ca2+ entry.
2008 Feb
Plasmodium falciparum regulatory subunit of cAMP-dependent PKA and anion channel conductance.
2008 Feb 8
Angiotensin II-stimulated Ca2+ entry mechanisms in afferent arterioles: role of transient receptor potential canonical channels and reverse Na+/Ca2+ exchange.
2008 Jan
Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells.
2008 Jul
Metabotropic receptor-activated calcium increases and store-operated calcium influx in mouse Müller cells.
2008 Jul
TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons.
2008 Jun 11
Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB).
2008 Mar
Role of iPLA2 and store-operated channels in agonist-induced Ca2+ influx and constriction in cerebral, mesenteric, and carotid arteries.
2008 Mar
Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway.
2008 Mar
Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells.
2008 Nov
Store-operated Ca2+ channels formed by TRPC1, TRPC6 and Orai1 and non-store-operated channels formed by TRPC3 are involved in the regulation of NADPH oxidase in HL-60 granulocytes.
2008 Nov
Sustained depolarization-induced propagation of [Ca2+]i oscillations in cultured DRG neurons: the involvement of extracellular ATP and P2Y receptor activation.
2008 Nov 6
Alcohol induces relaxation of rat thoracic aorta and mesenteric arterial bed.
2008 Sep-Oct
Two chromogranin a-derived peptides induce calcium entry in human neutrophils by calmodulin-regulated calcium independent phospholipase A2.
2009
The muscarinic M1 receptor activates Nrf2 through a signaling cascade that involves protein kinase C and inhibition of GSK-3beta: connecting neurotransmission with neuroprotection.
2009 Aug
Clodronate-induced cell apoptosis in human thyroid carcinoma is mediated via the P2 receptor signaling pathway.
2009 Aug
Signaling pathways from cannabinoid receptor-1 activation to inhibition of N-methyl-D-aspartic acid mediated calcium influx and neurotoxicity in dorsal root ganglion neurons.
2009 Dec
Transient receptor potential canonical type 3 channels and blood pressure in humans.
2009 Jun
N-acyldopamines control striatal input terminals via novel ligand-gated cation channels.
2009 Mar
Kisspeptin-10 facilitates a plasma membrane-driven calcium oscillator in gonadotropin-releasing hormone-1 neurons.
2009 Mar
Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus.
2009 Mar 15
Role of 5-hydroxytryptamine2C receptors in Ca2+-dependent ethanol potentiation of GABA release onto ventral tegmental area dopamine neurons.
2009 May
Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay.
2009 May 8
In vitro vasorelaxation mechanisms of bioactive compounds extracted from Hibiscus sabdariffa on rat thoracic aorta.
2009 Nov 2
Prostaglandin EP3 receptor superactivates adenylyl cyclase via the Gq/PLC/Ca2+ pathway in a lipid raft-dependent manner.
2009 Nov 27
Trichlorfon induces apoptosis in SH-SY5Y neuroblastoma cells via the endoplasmic reticulum?
2009 Sep 14
Signal transduction mechanisms underlying group I mGluR-mediated increase in frequency and amplitude of spontaneous EPSCs in the spinal trigeminal subnucleus oralis of the rat.
2009 Sep 2
Mechanisms of action of hydrogen sulfide in relaxation of mouse distal colonic smooth muscle.
2010 Feb 25
Glucose enhances expression of TRPC1 and calcium entry in endothelial cells.
2010 Jan
Characterization of spontaneous inhibitory postsynaptic currents in cultured rat retinal amacrine cells.
2010 Jan 20
NO contributes to abnormal vascular calcium regulation and reactivity induced by peritonitis-associated septic shock in rats.
2010 May
Increased rhythmicity in hypertensive arterial smooth muscle is linked to transient receptor potential canonical channels.
2010 Oct
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:21:23 GMT 2023
Edited
by admin
on Sat Dec 16 08:21:23 GMT 2023
Record UNII
E4ES684O93
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2-AMINOETHOXYDIPHENYLBORATE
Common Name English
BORINIC ACID, B,B-DIPHENYL-, 2-AMINOETHYL ESTER
Systematic Name English
DIPHENYL(2-AMINOETHOXY)BORANE
Systematic Name English
2-AMINOETHYL DIPHENYLBORINATE
Systematic Name English
ETHANOL, 2-AMINO-, DIPHENYLBORINATE (ESTER)
Common Name English
BORINIC ACID, DIPHENYL-, 2-AMINOETHYL ESTER
Systematic Name English
2-(DIPHENYLBORYLOXY)ETHYLAMINE
Systematic Name English
NSC-17107
Code English
NATURAL PRODUCT REAGENT A
Common Name English
BORINIC ACID, O-(2-AMINOETHYL)DIPHENYL-
Systematic Name English
DIPHENYLBORINIC ACID 2-AMINOETHYL ESTER
Systematic Name English
2-DIPHENYLBORANYLOXYETHANAMINE
Systematic Name English
J42.786A
Code English
NATURSTOFFREAGENZ A
Common Name English
2-APB
Common Name English
2-AMINOETHOXYDIPHENYL BORATE
Systematic Name English
(2-AMINOETHYLOXY)DIPHENYLBORANE
Systematic Name English
C20698
Code English
Code System Code Type Description
WIKIPEDIA
2-Aminoethoxydiphenyl borate
Created by admin on Sat Dec 16 08:21:23 GMT 2023 , Edited by admin on Sat Dec 16 08:21:23 GMT 2023
PRIMARY
NSC
17107
Created by admin on Sat Dec 16 08:21:23 GMT 2023 , Edited by admin on Sat Dec 16 08:21:23 GMT 2023
PRIMARY
FDA UNII
E4ES684O93
Created by admin on Sat Dec 16 08:21:23 GMT 2023 , Edited by admin on Sat Dec 16 08:21:23 GMT 2023
PRIMARY
ECHA (EC/EINECS)
208-366-5
Created by admin on Sat Dec 16 08:21:23 GMT 2023 , Edited by admin on Sat Dec 16 08:21:23 GMT 2023
PRIMARY
CAS
524-95-8
Created by admin on Sat Dec 16 08:21:23 GMT 2023 , Edited by admin on Sat Dec 16 08:21:23 GMT 2023
PRIMARY
EPA CompTox
DTXSID0040389
Created by admin on Sat Dec 16 08:21:23 GMT 2023 , Edited by admin on Sat Dec 16 08:21:23 GMT 2023
PRIMARY
PUBCHEM
1598
Created by admin on Sat Dec 16 08:21:23 GMT 2023 , Edited by admin on Sat Dec 16 08:21:23 GMT 2023
PRIMARY