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Details

Stereochemistry ACHIRAL
Molecular Formula C14H16BNO
Molecular Weight 225.094
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-AMINOETHOXYDIPHENYLBORATE

SMILES

NCCOB(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=BLZVCIGGICSWIG-UHFFFAOYSA-N
InChI=1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2

HIDE SMILES / InChI

Molecular Formula C14H16BNO
Molecular Weight 225.094
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Increased rhythmicity in hypertensive arterial smooth muscle is linked to transient receptor potential canonical channels.
2010-10
NO contributes to abnormal vascular calcium regulation and reactivity induced by peritonitis-associated septic shock in rats.
2010-05
Mechanisms of action of hydrogen sulfide in relaxation of mouse distal colonic smooth muscle.
2010-02-25
Characterization of spontaneous inhibitory postsynaptic currents in cultured rat retinal amacrine cells.
2010-01-20
Glucose enhances expression of TRPC1 and calcium entry in endothelial cells.
2010-01
Signaling pathways from cannabinoid receptor-1 activation to inhibition of N-methyl-D-aspartic acid mediated calcium influx and neurotoxicity in dorsal root ganglion neurons.
2009-12
Prostaglandin EP3 receptor superactivates adenylyl cyclase via the Gq/PLC/Ca2+ pathway in a lipid raft-dependent manner.
2009-11-27
In vitro vasorelaxation mechanisms of bioactive compounds extracted from Hibiscus sabdariffa on rat thoracic aorta.
2009-11-02
Trichlorfon induces apoptosis in SH-SY5Y neuroblastoma cells via the endoplasmic reticulum?
2009-09-14
Signal transduction mechanisms underlying group I mGluR-mediated increase in frequency and amplitude of spontaneous EPSCs in the spinal trigeminal subnucleus oralis of the rat.
2009-09-02
The muscarinic M1 receptor activates Nrf2 through a signaling cascade that involves protein kinase C and inhibition of GSK-3beta: connecting neurotransmission with neuroprotection.
2009-08
Clodronate-induced cell apoptosis in human thyroid carcinoma is mediated via the P2 receptor signaling pathway.
2009-08
Transient receptor potential canonical type 3 channels and blood pressure in humans.
2009-06
Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay.
2009-05-08
Role of 5-hydroxytryptamine2C receptors in Ca2+-dependent ethanol potentiation of GABA release onto ventral tegmental area dopamine neurons.
2009-05
Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus.
2009-03-15
N-acyldopamines control striatal input terminals via novel ligand-gated cation channels.
2009-03
Kisspeptin-10 facilitates a plasma membrane-driven calcium oscillator in gonadotropin-releasing hormone-1 neurons.
2009-03
Two chromogranin a-derived peptides induce calcium entry in human neutrophils by calmodulin-regulated calcium independent phospholipase A2.
2009
Initial and extended inflammatory messages of the nongenomic signaling pathway of the TCDD-activated Ah receptor in U937 macrophages.
2008-12-15
Activation of the aryl hydrocarbon receptor by the calcium/calmodulin-dependent protein kinase kinase inhibitor 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid (STO-609).
2008-12
Sustained depolarization-induced propagation of [Ca2+]i oscillations in cultured DRG neurons: the involvement of extracellular ATP and P2Y receptor activation.
2008-11-06
Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells.
2008-11
Store-operated Ca2+ channels formed by TRPC1, TRPC6 and Orai1 and non-store-operated channels formed by TRPC3 are involved in the regulation of NADPH oxidase in HL-60 granulocytes.
2008-11
Oxygen-regulated protein-150 prevents calcium homeostasis deregulation and apoptosis induced by oxidized LDL in vascular cells.
2008-08
Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells.
2008-07
Metabotropic receptor-activated calcium increases and store-operated calcium influx in mouse Müller cells.
2008-07
TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons.
2008-06-11
Alcohol induces relaxation of rat thoracic aorta and mesenteric arterial bed.
2008-05-23
A nitric oxide/Ca(2+)/calmodulin/ERK1/2 mitogen-activated protein kinase pathway is involved in the mitogenic effect of IL-1beta in human astrocytoma cells.
2008-04
Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB).
2008-03
Role of iPLA2 and store-operated channels in agonist-induced Ca2+ influx and constriction in cerebral, mesenteric, and carotid arteries.
2008-03
Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway.
2008-03
Plasmodium falciparum regulatory subunit of cAMP-dependent PKA and anion channel conductance.
2008-02-08
Inhibition of transient receptor potential canonical channels impairs cytokinesis in human malignant gliomas.
2008-02
Low concentrations of sphingosylphosphorylcholine enhance pulmonary artery vasoreactivity: the role of protein kinase C delta and Ca2+ entry.
2008-02
Angiotensin II-stimulated Ca2+ entry mechanisms in afferent arterioles: role of transient receptor potential canonical channels and reverse Na+/Ca2+ exchange.
2008-01
Human malarial parasite, Plasmodium falciparum, displays capacitative calcium entry: 2-aminoethyl diphenylborinate blocks the signal transduction pathway of melatonin action on the P. falciparum cell cycle.
2007-11
Pharmacological characterization and molecular determinants of the activation of transient receptor potential V2 channel orthologs by 2-aminoethoxydiphenyl borate.
2007-11
Ca2+-dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides.
2007-10-15
Monocytes from spontaneously hypertensive rats show increased store-operated and second messenger-operated calcium influx mediated by transient receptor potential canonical Type 3 channels.
2007-10
Role of TRPV1 and intracellular Ca2+ in excitation of cardiac sensory neurons by bradykinin.
2007-07
Non-genomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor.
2007-05-29
Activation properties of heterologously expressed mammalian TRPV2: evidence for species dependence.
2007-05-25
Metabotropic glutamate receptors in the lateral superior olive activate TRP-like channels: age- and experience-dependent regulation.
2007-05
2-Aminoethoxydiphenylborane is an acute inhibitor of directly photosensitive retinal ganglion cell activity in vitro and in vivo.
2007-04-11
Increased store-operated and 1-oleoyl-2-acetyl-sn-glycerol-induced calcium influx in monocytes is mediated by transient receptor potential canonical channels in human essential hypertension.
2007-04
Third activity of Bordetella adenylate cyclase (AC) toxin-hemolysin. Membrane translocation of AC domain polypeptide promotes calcium influx into CD11b+ monocytes independently of the catalytic and hemolytic activities.
2007-02-02
2-Aminoethyl diphenylborinate analogues: selective inhibition for store-operated Ca2+ entry.
2007-01-12
Calcium-sensing receptor stimulation induces nonselective cation channel activation in breast cancer cells.
2006
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:01:22 GMT 2025
Edited
by admin
on Mon Mar 31 22:01:22 GMT 2025
Record UNII
E4ES684O93
Record Status Validated (UNII)
Record Version
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Name Type Language
2-AMINOETHOXYDIPHENYLBORATE
Common Name English
C20698
Preferred Name English
BORINIC ACID, B,B-DIPHENYL-, 2-AMINOETHYL ESTER
Systematic Name English
DIPHENYL(2-AMINOETHOXY)BORANE
Systematic Name English
2-AMINOETHYL DIPHENYLBORINATE
Systematic Name English
ETHANOL, 2-AMINO-, DIPHENYLBORINATE (ESTER)
Common Name English
BORINIC ACID, DIPHENYL-, 2-AMINOETHYL ESTER
Systematic Name English
2-(DIPHENYLBORYLOXY)ETHYLAMINE
Systematic Name English
NSC-17107
Code English
NATURAL PRODUCT REAGENT A
Common Name English
BORINIC ACID, O-(2-AMINOETHYL)DIPHENYL-
Systematic Name English
DIPHENYLBORINIC ACID 2-AMINOETHYL ESTER
Systematic Name English
2-DIPHENYLBORANYLOXYETHANAMINE
Systematic Name English
J42.786A
Code English
NATURSTOFFREAGENZ A
Common Name English
2-APB
Common Name English
2-AMINOETHOXYDIPHENYL BORATE
Systematic Name English
(2-AMINOETHYLOXY)DIPHENYLBORANE
Systematic Name English
Code System Code Type Description
WIKIPEDIA
2-Aminoethoxydiphenyl borate
Created by admin on Mon Mar 31 22:01:22 GMT 2025 , Edited by admin on Mon Mar 31 22:01:22 GMT 2025
PRIMARY
NSC
17107
Created by admin on Mon Mar 31 22:01:22 GMT 2025 , Edited by admin on Mon Mar 31 22:01:22 GMT 2025
PRIMARY
FDA UNII
E4ES684O93
Created by admin on Mon Mar 31 22:01:22 GMT 2025 , Edited by admin on Mon Mar 31 22:01:22 GMT 2025
PRIMARY
ECHA (EC/EINECS)
208-366-5
Created by admin on Mon Mar 31 22:01:22 GMT 2025 , Edited by admin on Mon Mar 31 22:01:22 GMT 2025
PRIMARY
CAS
524-95-8
Created by admin on Mon Mar 31 22:01:22 GMT 2025 , Edited by admin on Mon Mar 31 22:01:22 GMT 2025
PRIMARY
EPA CompTox
DTXSID0040389
Created by admin on Mon Mar 31 22:01:22 GMT 2025 , Edited by admin on Mon Mar 31 22:01:22 GMT 2025
PRIMARY
PUBCHEM
1598
Created by admin on Mon Mar 31 22:01:22 GMT 2025 , Edited by admin on Mon Mar 31 22:01:22 GMT 2025
PRIMARY