U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:07:14 GMT 2023
Edited
by admin
on Sat Dec 16 14:07:14 GMT 2023
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
E2UJ1FS3EI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1
Common Name English
GASTRIC H(+)/K(+) ATPASE SUBUNIT ALPHA
Common Name English
Gastric proton pump component
Common Name English
Code System Code Type Description
FDA UNII
E2UJ1FS3EI
Created by admin on Sat Dec 16 14:07:16 GMT 2023 , Edited by admin on Sat Dec 16 14:07:16 GMT 2023
PRIMARY
UNIPROT
P20648
Created by admin on Sat Dec 16 14:07:16 GMT 2023 , Edited by admin on Sat Dec 16 14:07:16 GMT 2023
PRIMARY
Glycosylation Link Type Site
N 1_226
N 1_494
N 1_731
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Binds to potassium site
REVERSIBLE
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
reversible and potassium-competitive manner with a potency of inhibition approximately 350 times higher than the proton pump inhibitor, lansoprazole.
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL