POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Jun 26 23:00:41 UTC 2021` Edited by `admin` on `Sat Jun 26 23:00:41 UTC 2021`
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	E2UJ1FS3EI
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1

Common Name

English

GASTRIC H(+)/K(+) ATPASE SUBUNIT ALPHA

Common Name

English

PROTON PUMP

Common Name

English

Code System Code Type Description

FDA UNII

E2UJ1FS3EI

Created by admin on Sat Jun 26 23:00:43 UTC 2021 , Edited by admin on Sat Jun 26 23:00:43 UTC 2021

PRIMARY

UNIPROT

P20648

Created by admin on Sat Jun 26 23:00:43 UTC 2021 , Edited by admin on Sat Jun 26 23:00:43 UTC 2021

PRIMARY

Glycosylation Link Type	Site
N	1_226
N	1_494
N	1_731

Related Record Type Details


					N3PA6559FT

INHIBITOR -> TARGET


					776Q6XX45J

INHIBITOR -> TARGET


					65JK8810RM

INHIBITOR -> TARGET


					BE52S2C1QT

INHIBITOR -> TARGET


					32828355LL

INHIBITOR -> TARGET


					UYE4T5I70X

DEXLANSOPRAZOLE

INHIBITOR -> TARGET


					D8TST4O562

INHIBITOR -> TARGET


					W6OO9ZB0FC

INHIBITOR -> TARGET


					3L36P16U4R

RABEPRAZOLE SODIUM

INHIBITOR -> TARGET


					0K5C5T2QPG

INHIBITOR -> TARGET


					1R5L3J156G

INHIBITOR -> TARGET

Comments:

reversible and potassium-competitive manner with a potency of inhibition approximately 350 times higher than the proton pump inhibitor, lansoprazole.


					KG60484QX9

INHIBITOR -> TARGET

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL