U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2Na.HO4P.12H2O
Molecular Weight 358.1422
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM PHOSPHATE, DIBASIC, DODECAHYDRATE

SMILES

O.O.O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O

InChI

InChIKey=DGLRDKLJZLEJCY-UHFFFAOYSA-L
InChI=1S/2Na.H3O4P.12H2O/c;;1-5(2,3)4;;;;;;;;;;;;/h;;(H3,1,2,3,4);12*1H2/q2*+1;;;;;;;;;;;;;/p-2

HIDE SMILES / InChI
Molecular Formula H3O4P
Molecular Weight 97.9952
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Phosphoric acid, also known as orthophosphoric acid, is used in dentistry and orthodontics to clean and roughen the surfaces of teeth where dental appliances or fillings will be placed. In addition, this acid is a part of product ProcalAmine, which is indicated for peripheral administration in adults to preserve body protein and improve nitrogen balance in well-nourished, mildly catabolic patients who require short-term parenteral nutrition. In combination with dextrose (glucose) and levulose (fructose), phosphoric acid relieves nausea due to upset stomach from intestinal flu, stomach flu, and food or drink indiscretions. In addition, homeopathic product, Brain power contains also phosphoric acid and this product is used to temporarily relieve symptoms of general physical weakness and listlessness, including: fatigue; sore muscles & joints; dry skin; absence of sexual desire; occasional sleeplessness.

Approval Year

1921
1467
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Approved
8429
PROCALAMINE

Approved Use

ProcalAmine is indicated for peripheral administration in adults to preserve body protein and improve nitrogen balance in well-nourished, mildly catabolic patients who require short-term parenteral nutrition.

Launch Date

1982
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Diagnostic
Natural Metabolite
Unknown

Approved Use

Unknown
Diagnostic
Natural Metabolite
Unknown

Approved Use

Unknown
Primary
Approved
8429
SODIUM PHOSPHATES INJECTION

Approved Use

Sodium Phosphates Injection, USP, 3mM P/mL, is indicated as a source of phosphorus, for addition to large volume intravenous fluids, to prevent or correct hypophosphatemia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions. The concomitant amount of sodium (4 mEq/mL) must be calculated into total electrolyte content of such prepared solutions.
PubMed

PubMed

TitleDatePubMed
Diurnal variation in the levels of glucose and related substances in healthy and diabetic subjects during starvation.
1967 Feb
Determination of inorganic phosphate in serum and saliva using a synthetic receptor.
2003 Jun 12
Amperometric biosensor for determining human salivary phosphate.
2005 Aug 15
Phosphorus amendment reduces hepatic and renal oxidative stress in mallards ingesting lead-contaminated sediments.
2006 Jun
Patents

Patents

04224407
30
04355158
29
04487752
28
04533660
37
04537718
27
04565680
30
04613463
35
04744965
27
04780452
28
04812462
29
04886910
30
05374392
27
05387697
27
05415807
29
05444050
28
05496930
27
05525524
27
05635391
27
05698229
27
05910504
29
05916781
27
05917041
35
05928933
27
05962694
28
05994368
29
06017919
28
06028035
27
06096689
27
06165944
27
06197973
27
06258829
27
06399627
28
06528514
27
06576596
27
06657060
27
06737417
27
06821980
27
06864367
28
06867198
27
06903217
29
06916837
27
06924310
28
06933365
27
06958347
27
06974639
27
06989391
31
06992087
30
07005440
29
07045551
27
07074801
32
07087609
27
07094801
30
07115611
29
07169944
27
07176216
27
07179912
27
07196081
32
07223762
27
07230023
29
07247731
40
07273882
27
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29
07317012
27
07323569
29
07332511
32
07338963
30
07345068
28
07354662
27
07432287
27
07432375
27
07439237
27
07446216
27
07449477
27
07456196
28
07456218
27
07507739
36
07517894
27
07524951
27
07531535
29
07544690
30
07560582
40
07563901
27
07582754
31
07582803
35
07589199
30
07592358
29
07595178
27
07595314
29
07632850
27
07655664
28
07700589
28
07737166
33
07749992
30
07772285
30
07829563
28
07834030
30
07906517
31
07947711
27
07951797
27
07968720
27
07994336
29
07998995
28
08008321
27
08017610
30
08039479
29
08063099
31
08067583
27
08080541
30
08143446
28
08153653
27
08173812
27
08173824
27
08211927
27
08221905
27
08273767
28
08304411
28
08313671
27
08324216
27
08324219
28
08372858
30
08377921
29
08394830
28
08394842
27
08399450
29
08404673
29
08415349
29
08415359
29
08436024
27
08481579
27
08492582
27
08497397
28
08501732
37
08524751
27
08524909
29
08536197
29
08546588
29
08569341
29
08586204
27
08591943
28
08609675
28
08618094
28
08629144
28
08633216
27
08658117
27
08674111
28
08674141
28
08680120
29
08703784
27
08709615
27
08791139
28
08841467
27
08846746
27
20020025910
30
20030003160
27
20120070359
27
20140171390
27
2600813
27
US3382035
27

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:58:33 GMT 2023
Edited
by admin
on Fri Dec 15 15:58:33 GMT 2023
Record UNII
E1W4N241FO
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM PHOSPHATE, DIBASIC DODECAHYDRATE
MI  
Preferred Name English
SODIUM PHOSPHATE, DIBASIC, DODECAHYDRATE
II  
Common Name English
PHOSPHORIC ACID DISODIUM DODECAHYDRATE
Systematic Name English
DISODIUM HYDROGEN PHOSPHATE, DODECAHYDRATE
Systematic Name English
DISODIUM PHOSPHATE DODECAHYDRATE [EP MONOGRAPH]
Common Name English
MONOSODIUM PHOSPHATE DODECAHYDRATE
Systematic Name English
DISODIUM PHOSPHATE (NA2HPO4.12H2O)
Common Name English
DISODIUM PHOSPHATE (NA2HPO4) DODECAHYDRATE
Common Name English
DISODIUM PHOSPHATE DODECAHYDRATE
EP  
Systematic Name English
DISODIUM HYDROGEN ORTHOPHOSPHATE DODECAHYDRATE
Systematic Name English
SODIUM PHOSPHATE, DIBASIC DODECAHYDRATE [MI]
Common Name English
DISODIUM ORTHOPHOSPHATE, DODECAHYDRATE
Systematic Name English
DIBASIC SODIUM PHOSPHATE HYDRATE [JAN]
Common Name English
SODIUM PHOSPHATE (NA2HPO4) DODECAHYDRATE
Common Name English
DISODIUM PHOSPHATE DODECAHYDRATE (NA2HPO4.12H2O)
Common Name English
Sodium phosphate dibasic dodecahydrate [WHO-DD]
Common Name English
DIBASIC SODIUM PHOSPHATE HYDRATE
Common Name English
MONOHYDROGEN DISODIUM PHOSPHATE DODECAHYDRATE
Common Name English
SODIUM PHOSPHATE, DIBASIC, DODECAHYDRATE [II]
Common Name English
PHOSPHORIC ACID, DISODIUM SALT, DODECAHYDRATE
Common Name English
DISODIUM PHOSPHATE DODECAHYDRATE [EP IMPURITY]
Common Name English
DIBASIC SODIUM PHOSPHATE, DODECAHYDRATE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29730
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
Code System Code Type Description
EVMPD
SUB11922MIG
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY
PUBCHEM
61456
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY
DAILYMED
E1W4N241FO
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY
FDA UNII
E1W4N241FO
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY
MERCK INDEX
m10059
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY Merck Index
RXCUI
1311326
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY RxNorm
SMS_ID
100000091452
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY
DRUG BANK
DBSALT001975
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY
CAS
10039-32-4
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY
EPA CompTox
DTXSID4064923
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY
NCI_THESAURUS
C66548
Created by admin on Fri Dec 15 15:58:33 GMT 2023 , Edited by admin on Fri Dec 15 15:58:33 GMT 2023
PRIMARY
Related Record Type Details
Structure of SODIUM PHOSPHATE, DIBASIC, ANHYDROUS
ANHYDROUS->SOLVATE
NIH
NCATS
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