Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H23NO3 |
| Molecular Weight | 241.3266 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1(C)CC(CC(C)(C)N1O)OC(=O)C2CC2
InChI
InChIKey=ZWEXEKJLDHNLLA-UHFFFAOYSA-N
InChI=1S/C13H23NO3/c1-12(2)7-10(8-13(3,4)14(12)16)17-11(15)9-5-6-9/h9-10,16H,5-8H2,1-4H3
| Molecular Formula | C13H23NO3 |
| Molecular Weight | 241.3266 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Othera Pharmaceuticals developed OT-551 as an antioxidant and anti-inflammatory agent. OT-551 downregulates the overexpression of the protein complex nuclear factor (NF)-kappa B. It is known that NF-kappa B is highly activated when oxidative stress, inflammation, and angiogenesis occurs. OT-551 was studied in phase II clinical trial for the treatment of age-related macular degeneration. In addition, the drug was studied for the treatment of cataracts and dry eyes; however, these studies were discontinued. Besides, phase II clinical trial for the treatment of geographic atrophy has shown that OT-551 might have limited or no benefit as a treatment for this disease.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 03:12:19 GMT 2023
by
admin
on
Sat Dec 16 03:12:19 GMT 2023
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| Record UNII |
DZ02S3A31N
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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DZ02S3A31N
Created by
admin on Sat Dec 16 03:12:19 GMT 2023 , Edited by admin on Sat Dec 16 03:12:19 GMT 2023
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10131000
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admin on Sat Dec 16 03:12:19 GMT 2023 , Edited by admin on Sat Dec 16 03:12:19 GMT 2023
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DB05650
Created by
admin on Sat Dec 16 03:12:19 GMT 2023 , Edited by admin on Sat Dec 16 03:12:19 GMT 2023
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627085-11-4
Created by
admin on Sat Dec 16 03:12:19 GMT 2023 , Edited by admin on Sat Dec 16 03:12:19 GMT 2023
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