U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:08:06 GMT 2023
Edited
by admin
on Sat Dec 16 15:08:06 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
DX0L1Z7JO9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ZAMEROVIMAB
INN  
Official Name English
SYN023 COMPONENT CTB-011
Code English
SYN-023 COMPONENT CTB-011
Code English
CTB-011
Code English
CTB011
Code English
IMMUNOGLOBULIN G1, ANTI-(RABIES LYSSAVIRUS SPIKE GLYCOPROTEIN G) (HUMAN-MUS MUSCULUS CLONE 1A9 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS CLONE 1A9 .KAPPA.-CHAIN, DIMER
Common Name English
zamerovimab [INN]
Common Name English
Code System Code Type Description
NCI_THESAURUS
C184875
Created by admin on Sat Dec 16 15:08:06 GMT 2023 , Edited by admin on Sat Dec 16 15:08:06 GMT 2023
PRIMARY
FDA UNII
DX0L1Z7JO9
Created by admin on Sat Dec 16 15:08:06 GMT 2023 , Edited by admin on Sat Dec 16 15:08:06 GMT 2023
PRIMARY
INN
11747
Created by admin on Sat Dec 16 15:08:06 GMT 2023 , Edited by admin on Sat Dec 16 15:08:06 GMT 2023
PRIMARY
CAS
2419087-87-7
Created by admin on Sat Dec 16 15:08:06 GMT 2023 , Edited by admin on Sat Dec 16 15:08:06 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_148 2_204
2_224 4_214
2_265 2_325
1_148 1_204
2_371 2_429
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_224 3_214
1_230 2_230
1_233 2_233
1_265 1_325
1_371 1_429
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_301
N 2_301
Related Record Type Details
TARGET ORGANISM->INHIBITOR
CTB011 and CTB012 are capable of mediating CDC and ADCC as a mechanism of clearing RABV.
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL