DIMETACRINE BITARTRATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H26N2.C4H6O6
Molecular Weight	444.5207
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CN(C)CCCN1C2=CC=CC=C2C(C)(C)C3=CC=CC=C13

InChI

InChIKey=IIYKUJVECNNTEY-LREBCSMRSA-N

InChI=1S/C20H26N2.C4H6O6/c1-20(2)16-10-5-7-12-18(16)22(15-9-14-21(3)4)19-13-8-6-11-17(19)20;5-1(3(7)8)2(6)4(9)10/h5-8,10-13H,9,14-15H2,1-4H3;1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1

HIDE SMILES / InChI

Molecular Formula	C4H6O6
Molecular Weight	150.0868
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	C20H26N2
Molecular Weight	294.4338
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6008540 | https://www.ncbi.nlm.nih.gov/pubmed/4149236 | https://www.ncbi.nlm.nih.gov/pubmed/1150371 | https://www.ncbi.nlm.nih.gov/pubmed/4463275

Dimetacrine is a tricyclic antidepressant. It has been used in the treatment of depressive states. Dimetacrine usage associates with risk of cardiovascular side effects.

CNS Activity

Approval Year

PubMed

Title	Date	PubMed
The pharmacological studies on dimetacrine. I. Studies on the absorption, distribution and excretion of H3-labeled dimetacrine in the rat.	1970 Sep	5312397

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:50:47 UTC 2023` Edited by `admin` on `Sat Dec 16 05:50:47 UTC 2023`
Record UNII	DVH164X0IF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIMETACRINE BITARTRATE

Common Name

English

SD-709

Code

English

10(9H)-ACRIDINEPROPANAMINE, N,N,9,9-TETRAMETHYL-, (R-(R*,R*))-2,3-DIHYDROXYBUTANEDIOATE (1:1)

Common Name

English

ACRIDAN, 10-(3-(DIMETHYLAMINO)PROPYL)-9,9-DIMETHYL-, TARTRATE (1:1)

Systematic Name

English

MO-709

Code

English

LINOSTIL

Brand Name

English

DIMETACRINE BITARTRATE [JAN]

Common Name

English

ISTONIL

Brand Name

English

DIMETACRINE TARTRATE [MI]

Common Name

English

MIROISTONIL

Brand Name

English

DIMETACRINE TARTRATE

Common Name

English

DIMETACRIN HYDROGENTARTRATE

Common Name

English

10(9H)-ACRIDINEPROPANAMINE, N,N,9,9-TETRAMETHYL-, (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE (1:1)

Systematic Name

English

Code System Code Type Description

MERCK INDEX

m1117