EGAPTIVON PEGOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 10:53:27 GMT 2023` Edited by `admin` on `Sat Dec 16 10:53:27 GMT 2023`
Nucleic Acid Type	OLIGONUCLEOTIDE
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	DT0445S65M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EGAPTIVON PEGOL

Official Name

English

ARC-1779

Code

English

ARC1779

Code

English

EGAPTIVON PEGOL [USAN]

Common Name

English

egaptivon pegol [INN]

Common Name

English

Egaptivon pegol [WHO-DD]

Common Name

English

Code System Code Type Description

DRUG BANK

DB05202

Created by admin on Sat Dec 16 10:53:28 GMT 2023 , Edited by admin on Sat Dec 16 10:53:28 GMT 2023

PRIMARY

USAN

UU-30

Created by admin on Sat Dec 16 10:53:28 GMT 2023 , Edited by admin on Sat Dec 16 10:53:28 GMT 2023

PRIMARY

FDA UNII

DT0445S65M

Created by admin on Sat Dec 16 10:53:28 GMT 2023 , Edited by admin on Sat Dec 16 10:53:28 GMT 2023

PRIMARY

CAS

934868-74-3

Created by admin on Sat Dec 16 10:53:28 GMT 2023 , Edited by admin on Sat Dec 16 10:53:28 GMT 2023

PRIMARY

ChEMBL

CHEMBL2108339

Created by admin on Sat Dec 16 10:53:28 GMT 2023 , Edited by admin on Sat Dec 16 10:53:28 GMT 2023

PRIMARY

NCI_THESAURUS

C95742

Created by admin on Sat Dec 16 10:53:28 GMT 2023 , Edited by admin on Sat Dec 16 10:53:28 GMT 2023

PRIMARY

INN

9264

Created by admin on Sat Dec 16 10:53:28 GMT 2023 , Edited by admin on Sat Dec 16 10:53:28 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methyl-Ribose	1_2-1_4;1_8-1_18;1_20;1_22;1_27-1_28;1_30;1_33-1_34;1_36-1_39	25 / 40
Deoxyribose (DNA)	1_5-1_7;1_19;1_21;1_23-1_26;1_29;1_31-1_32;1_35;1_40	14 / 40
D-Ribose (RNA)	1_1	1 / 40

Linkage	Site Range	Site Count
Phosporothioate	1_21	1 / 39
Phosphate	1_2-1_20;1_22-1_40	38 / 39

Related Record Type Details


					DT0445S65M

EGAPTIVON PEGOL

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_40]	3'-TERMINUS			THYMIDINE 3'-MONOPHOSPHATE	Q84LAH3NDH
NUCLEOTIDE SUBSTITUTION	[1_1]				UNSPECIFIED SUBSTANCE	a9936b21 (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL