Approval Year
| Substance Class |
Nucleic Acid
Created
by
admin
on
Edited
Sat Dec 16 13:39:13 GMT 2023
by
admin
on
Sat Dec 16 13:39:13 GMT 2023
|
| Nucleic Acid Type | OLIGONUCLEOTIDE |
| Nucleic Acid Subtype | ANTI-SENSE |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
DR9CF3915M
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Official Name | English | ||
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Code | English | ||
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Common Name | English | ||
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Code | English | ||
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Code | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
FDA ORPHAN DRUG |
457914
Created by
admin on Sat Dec 16 13:39:13 GMT 2023 , Edited by admin on Sat Dec 16 13:39:13 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
10433
Created by
admin on Sat Dec 16 13:39:13 GMT 2023 , Edited by admin on Sat Dec 16 13:39:13 GMT 2023
|
PRIMARY | |||
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DR9CF3915M
Created by
admin on Sat Dec 16 13:39:13 GMT 2023 , Edited by admin on Sat Dec 16 13:39:13 GMT 2023
|
PRIMARY | |||
|
CD-183
Created by
admin on Sat Dec 16 13:39:13 GMT 2023 , Edited by admin on Sat Dec 16 13:39:13 GMT 2023
|
PRIMARY | |||
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121494124
Created by
admin on Sat Dec 16 13:39:13 GMT 2023 , Edited by admin on Sat Dec 16 13:39:13 GMT 2023
|
PRIMARY | |||
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1698048-23-5
Created by
admin on Sat Dec 16 13:39:13 GMT 2023 , Edited by admin on Sat Dec 16 13:39:13 GMT 2023
|
PRIMARY | |||
|
C169801
Created by
admin on Sat Dec 16 13:39:13 GMT 2023 , Edited by admin on Sat Dec 16 13:39:13 GMT 2023
|
PRIMARY |
| Sugar | Site Range | Site Count |
|---|---|---|
| 2'-O-Methoxyethyl ribose | 1_1-1_2;1_15-1_16 | 4 / 16 |
| 1_3-1_4;1_13-1_14 | 4 / 16 | |
| Deoxyribose (DNA) | 1_5-1_12 | 8 / 16 |
| Linkage | Site Range | Site Count |
|---|---|---|
| Phosporothioate | 1_2-1_16 | 15 / 15 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET->INHIBITOR OF EXPRESSION |
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|
|
SALT/SOLVATE -> PARENT |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
|
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| NUCLEOSIDE_SUBSTITUTION | [1_2] [1_15] | SITE_SPECIFIC | 2'-O-(2-METHOXYETHYL)-5-METHYLCYTIDINE | AOQ54IZZ6J | ||
| NUCLEOSIDE_SUBSTITUTION | [1_1] | SITE_SPECIFIC | 2'-O-(2-METHOXYETHYL)-5-METHYLURIDINE | 9Q36I4D9VB | ||
| NUCLEOSIDE_SUBSTITUTION | [1_3] [1_4] [1_11] [1_12] | SITE_SPECIFIC | 2'-O,4'-C-((1S)-ETHANE-1,1-DIYL).BETA.-D-RIBOSE 5-METHYL CYTIDINE | 7XRE49320R |