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Details

Stereochemistry ACHIRAL
Molecular Formula C6H5O7.C5H14NO.2H
Molecular Weight 295.2868
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHOLINE DIHYDROGEN CITRATE

SMILES

C(C(=O)O)C(CC(=O)[O-])(C(=O)O)O.C[N+](C)(C)CCO

InChI

InChIKey=WRPUOFKIGGWQIJ-UHFFFAOYSA-M
InChI=1S/C6H8O7.C5H14NO/c7-3(8)1-6(13,5(11)12)2-4(9)10;1-6(2,3)4-5-7/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);7H,4-5H2,1-3H3/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula H
Molecular Weight 1.0079
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C5H14NO
Molecular Weight 104.171
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H5O7
Molecular Weight 189.1
Charge -3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

TRICHOLINE CITRATE is indicated for the treatment and management of hepatic disorders and asthma symptoms in adults. It exerts lipotropic action in the hepatic cells. It also can lower the symptoms of asthma and reducing the pro-inflammatory and inflammatory mediators of the leukotriene pathway.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Cypron

Approved Use

Cyproheptadine Tricholine Citrate & Sorbitol Syrup is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: · Occasional Constipation · Liver Disorders · Asthma Symptoms In Adults · Allergic Reactions · Seasonal Allergies · Mild And Uncomplicated Hives
Primary
Cypron

Approved Use

Cyproheptadine Tricholine Citrate & Sorbitol Syrup is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: · Occasional Constipation · Liver Disorders · Asthma Symptoms In Adults · Allergic Reactions · Seasonal Allergies · Mild And Uncomplicated Hives
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG



OverviewOther

Other InhibitorOther SubstrateOther Inducer









Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
moderate
moderate
moderate
no [Activation >10 uM]
no [Activation >10 uM]
no [Activation >10 uM]
no [Activation >10 uM]
no [Activation >10 uM]
no
yes
Drug as victim
Substance Class Chemical
Created
by admin
on Sat Jun 26 00:38:30 UTC 2021
Edited
by admin
on Sat Jun 26 00:38:30 UTC 2021
Record UNII
DQ8HHP07GL
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CHOLINE DIHYDROGEN CITRATE
MI   WHO-DD  
Systematic Name English
CHOLINE, CITRATE (1:1) (SALT)
Common Name English
ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, SALT WITH 2-HYDROXY-1,2,3-PROPANETRICARBOXYLIC ACID
Common Name English
CHOLINE DIHYDROGEN CITRATE [MI]
Common Name English
CHOLINE DIHYDROGEN CITRATE [WHO-DD]
Common Name English
CITRIC ACID, ION(1-), CHOLINE
Common Name English
1,2,3-PROPANETRICARBOXYLIC ACID, 2-HYDROXY-, ION(1-), 2-HYDROXY-N,N,N-TRIMETHYLETHANAMINIUM
Common Name English
2-HYDROXYETHYLTRIMETHYLAMMONIUM DIHYDROGEN CITRATE
Systematic Name English
ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1)
Systematic Name English
ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, SALT WITH 2-HYDROXY-1,2,3-PROPANETRICARBOXYLIC ACID (1:1)
Common Name English
Code System Code Type Description
ChEMBL
CHEMBL2104477
Created by admin on Sat Jun 26 00:38:30 UTC 2021 , Edited by admin on Sat Jun 26 00:38:30 UTC 2021
PRIMARY
CAS
77-91-8
Created by admin on Sat Jun 26 00:38:30 UTC 2021 , Edited by admin on Sat Jun 26 00:38:30 UTC 2021
PRIMARY
MERCK INDEX
M3481
Created by admin on Sat Jun 26 00:38:30 UTC 2021 , Edited by admin on Sat Jun 26 00:38:30 UTC 2021
PRIMARY Merck Index
FDA UNII
DQ8HHP07GL
Created by admin on Sat Jun 26 00:38:30 UTC 2021 , Edited by admin on Sat Jun 26 00:38:30 UTC 2021
PRIMARY
PUBCHEM
66170
Created by admin on Sat Jun 26 00:38:30 UTC 2021 , Edited by admin on Sat Jun 26 00:38:30 UTC 2021
PRIMARY
ECHA (EC/EINECS)
201-068-6
Created by admin on Sat Jun 26 00:38:30 UTC 2021 , Edited by admin on Sat Jun 26 00:38:30 UTC 2021
PRIMARY
EVMPD
SUB13352MIG
Created by admin on Sat Jun 26 00:38:30 UTC 2021 , Edited by admin on Sat Jun 26 00:38:30 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE