U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 19:21:25 GMT 2023
Edited
by admin
on Sat Dec 16 19:21:25 GMT 2023
Protein Type RECEPTOR
Protein Sub Type CYTOKINE RECEPTOR
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
DN82J7Z829
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Interleukin-2 receptor subunit beta and gamma complex
Common Name English
IL-2 receptor beta and gamma subunits
Common Name English
Code System Code Type Description
FDA UNII
DN82J7Z829
Created by admin on Sat Dec 16 19:21:25 GMT 2023 , Edited by admin on Sat Dec 16 19:21:25 GMT 2023
PRIMARY
UNIPROT
P14784
Created by admin on Sat Dec 16 19:21:25 GMT 2023 , Edited by admin on Sat Dec 16 19:21:25 GMT 2023
PRIMARY
UNIPROT
P31785
Created by admin on Sat Dec 16 19:21:25 GMT 2023 , Edited by admin on Sat Dec 16 19:21:25 GMT 2023
PRIMARY
From To
1_48 1_60
1_33 1_84
2_160 2_209
2_80 2_93
2_40 2_50
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_3
N 1_17
N 1_45
N 1_123
N 1_326
N 2_2
N 2_49
N 2_53
N 2_62
N 2_137
N 2_227
Related Record Type Details
LIGAND->TARGET
AGONIST -> TARGET
SHR-1501 activates and increases the levels of natural killer (NK) cells and memory CD8+ T-cells without stimulating regulatory T-cells (Tregs).
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL