Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C12H22O11.H2O |
Molecular Weight | 360.3118 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 9 / 9 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
O.OC[C@@H](O)[C@@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O
InChI
InChIKey=HBDJFVFTHLOSDW-DNDLZOGFSA-N
InChI=1S/C12H22O11.H2O/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12;/h1,4-12,14-21H,2-3H2;1H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+;/m0./s1
Molecular Formula | C12H22O11 |
Molecular Weight | 342.2965 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 9 / 9 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Molecular Formula | H2O |
Molecular Weight | 18.0153 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Maltose, a disaccharide, is found mainly in grains and cereals. Nutritionally, maltose provides the same number of calories as starches and other sugars. Maltose can be the agent responsible for the primary signals to induce the sensations of hunger and satiation in human beings. It was shown, that parenterally administered maltose could be of clinical value.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: CHEMBL2074 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16702880 |
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Target ID: CHEMBL2608 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1058500 |
PubMed
Title | Date | PubMed |
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Kinetic analysis of the liver-type (GLUT2) and brain-type (GLUT3) glucose transporters in Xenopus oocytes: substrate specificities and effects of transport inhibitors. | 1993 Mar 15 |
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Catalytic mechanism of beta-amylase from Bacillus cereus var. mycoides: chemical rescue of hydrolytic activity for a catalytic site mutant (Glu367-->Ala) by azide. | 2002 Apr |
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Structural evidence for a dominant role of nonpolar interactions in the binding of a transport/chemosensory receptor to its highly polar ligands. | 2002 Jan 22 |
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Emended descriptions of the genus Micrococcus, Micrococcus luteus (Cohn 1872) and Micrococcus lylae (Kloos et al. 1974). | 2002 Mar |
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Crystal structure of AlgQ2, a macromolecule (alginate)-binding protein of Sphingomonas sp. A1 at 2.0A resolution. | 2002 Mar 8 |
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Large-scale purification, dissociation and functional reassembly of the maltose ATP-binding cassette transporter (MalFGK(2)) of Salmonella typhimurium. | 2002 Sep 20 |
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Physiological function of the maltose operon regulator, MalR, in Lactococcus lactis. | 2002 Sep 25 |
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[Calorimetric study of the interaction between amino acids and sugars in water at 298.15 K]. | 2003 Jul-Aug |
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Thermomonas hydrothermalis sp. nov., a new slightly thermophilic gamma-proteobacterium isolated from a hot spring in central Portugal. | 2003 Mar |
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Nonnatural branched polysaccharides: synthesis and properties of chitin and chitosan having disaccharide maltose branches. | 2003 Sep-Oct |
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Synthesis and hemolytic activity of some hederagenin diglycosides. | 2004 Aug |
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Maltose is the major form of carbon exported from the chloroplast at night. | 2004 Jan |
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X-ray structures of the maltose-maltodextrin-binding protein of the thermoacidophilic bacterium Alicyclobacillus acidocaldarius provide insight into acid stability of proteins. | 2004 Jan 2 |
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Maltose-binding protein is open in the catalytic transition state for ATP hydrolysis during maltose transport. | 2004 Jul 2 |
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Comparative study of the composition of melanoidins from glucose and maltose. | 2004 Jun 30 |
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Functional reconstitution of a maltose ATP-binding cassette transporter from the thermoacidophilic gram-positive bacterium Alicyclobacillus acidocaldarius. | 2004 May 12 |
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Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers. | 2005 Nov 14 |
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Molecular recognition of mono- and disaccharides through interaction with p-iodophenylboronic acid in capillary electrophoresis with a chemiluminescence detection system. | 2006 Aug 4 |
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Selective, reversible, reagentless maltose biosensing with core-shell semiconducting nanoparticles. | 2006 Feb |
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Controlled release of saccharides from matrix tablets. | 2006 Feb |
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ATP induces conformational changes of periplasmic loop regions of the maltose ATP-binding cassette transporter. | 2006 Feb 17 |
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Topography of the surface of the signal-transducing protein EIIA(Glc) that interacts with the MalK subunits of the maltose ATP-binding cassette transporter (MalFGK2) of Salmonella typhimurium. | 2006 May 5 |
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Direct C-glycosylation of indole with unprotected mono-, di-, and trisaccharides: a one-pot synthesis of 1-deoxy-1,1-bis(3-indolyl)alditols. | 2006 Nov 27 |
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Genetic basis for resistance to gel baits, fipronil, and sugar-based attractants in German cockroaches (Dictyoptera: blattellidae). | 2006 Oct |
|
The taxonomy of Enterobacter sakazakii: proposal of a new genus Cronobacter gen. nov. and descriptions of Cronobacter sakazakii comb. nov. Cronobacter sakazakii subsp. sakazakii, comb. nov., Cronobacter sakazakii subsp. malonaticus subsp. nov., Cronobacter turicensis sp. nov., Cronobacter muytjensii sp. nov., Cronobacter dublinensis sp. nov. and Cronobacter genomospecies 1. | 2007 Apr 17 |
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ATP-driven MalK dimer closure and reopening and conformational changes of the "EAA" motifs are crucial for function of the maltose ATP-binding cassette transporter (MalFGK2). | 2007 Aug 3 |
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Kinetic and structural analysis of enzyme sliding on a substrate: multiple attack in beta-amylase. | 2007 Jan 23 |
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Mapping putative contact sites between subunits in a bacterial ATP-binding cassette (ABC) transporter by synthetic peptide libraries. | 2007 Jun 1 |
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Correlated ab initio quantum chemical calculations of di- and trisaccharide conformations. | 2007 Sep |
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Proteome analysis of Aspergillus niger: lactate added in starch-containing medium can increase production of the mycotoxin fumonisin B2 by modifying acetyl-CoA metabolism. | 2009 Dec 10 |
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Crystal structures of the solute receptor GacH of Streptomyces glaucescens in complex with acarbose and an acarbose homolog: comparison with the acarbose-loaded maltose-binding protein of Salmonella typhimurium. | 2010 Apr 2 |
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Isolation and characterization of lactic acid bacteria strains with ornithine producing capacity from natural sea salt. | 2010 Aug |
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Enhancement of avermectin and ivermectin production by overexpression of the maltose ATP-binding cassette transporter in Streptomyces avermitilis. | 2010 Dec |
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Microbial and bioconversion production of D-xylitol and its detection and application. | 2010 Dec 15 |
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Constructing fluorogenic Bacillus spores (F-spores) via hydrophobic decoration of coat proteins. | 2010 Feb 19 |
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Complete (1)H resonance assignment of beta-maltose from (1)H-(1)H DQ-SQ CRAMPS and (1)H (DQ-DUMBO)-(13)C SQ refocused INEPT 2D solid-state NMR spectra and first principles GIPAW calculations. | 2010 Jul 14 |
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Live recombinant Salmonella Typhi vaccines constructed to investigate the role of rpoS in eliciting immunity to a heterologous antigen. | 2010 Jun 18 |
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Molecular composition of staufen2-containing ribonucleoproteins in embryonic rat brain. | 2010 Jun 28 |
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Optimization of culture media for enhanced chitinase production from a novel strain of Stenotrophomonas maltophilia using response surface methodology. | 2010 Nov |
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Dissolution-accompanied aggregation kinetics of silver nanoparticles. | 2010 Nov 16 |
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Dissection of an old protein reveals a novel application: domain D of Staphylococcus aureus Protein A (sSpAD) as a secretion--tag. | 2010 Nov 23 |
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Differential proteomic analysis highlights metabolic strategies associated with balhimycin production in Amycolatopsis balhimycina chemostat cultivations. | 2010 Nov 26 |
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Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509). | 2010 Nov 30 |
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The maltose ATP-binding cassette transporter in the 21st century--towards a structural dynamic perspective on its mode of action. | 2010 Sep |
|
Unconventional layer-by-layer assembly of graphene multilayer films for enzyme-based glucose and maltose biosensing. | 2010 Sep 21 |
Patents
Substance Class |
Chemical
Created
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Edited
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Record UNII |
DM477EE40D
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C68472
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SUB91617
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6363-53-7
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1375025
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1311260
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100000141342
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DM477EE40D
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23615261
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C80300
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DM477EE40D
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Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE | |||
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ANHYDROUS->SOLVATE |