HYDRARGAPHEN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H14O6S2.2C6H5Hg
Molecular Weight	981.85
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Hg+]C1=CC=CC=C1.[Hg+]C2=CC=CC=C2.[O-]S(=O)(=O)C3=CC4=CC=CC=C4C=C3CC5=C(C=C6C=CC=CC6=C5)S([O-])(=O)=O

InChI

InChIKey=KDNVJBRRDKAHDA-UHFFFAOYSA-L

InChI=1S/C21H16O6S2.2C6H5.2Hg/c22-28(23,24)20-12-16-7-3-1-5-14(16)9-18(20)11-19-10-15-6-2-4-8-17(15)13-21(19)29(25,26)27;2*1-2-4-6-5-3-1;;/h1-10,12-13H,11H2,(H,22,23,24)(H,25,26,27);2*1-5H;;/q;;;2*+1/p-2

HIDE SMILES / InChI

Molecular Formula	C21H14O6S2
Molecular Weight	426.462
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C6H5Hg
Molecular Weight	277.69
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14066172 | https://www.ncbi.nlm.nih.gov/pubmed/14858885

Hydrargaphen (also known as penotrane) was studied in trials for patients with herpes genitalia. In the treatment of Trichomonas vaginalis infections, penotrane was the suitable treatment for those patients who have not responded to other treatments. Information about the current use of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Trichomonas vaginalis infections treated with "penotrane".	1951 Aug 25	14858885
HERPES GENITALIS. SURVEY OF THIRTY CASES AND EFFECT OF TREATMENT WITH "PENOTRANE" JELLY.	1963 Sep	14066172
Comparison of nystatin ('Nystan') and hydrargaphen ('Penotrane') in the treatment of vaginal candidosis in pregnancy.	1973	4591821

Sample Use Guides

In Vivo Use Guide

The patient was instructed to apply the jelly liberally twice a day to the lesions and to return after 3 days and after 7 days of treatment.

Route of Administration: Topical

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:30:14 GMT 2023` Edited by `admin` on `Fri Dec 15 17:30:14 GMT 2023`
Record UNII	DL2D409P9O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

HYDRARGAPHEN

Official Name

English

(.MU.-((3,3'-METHYLENEBIS(2-NAPHTHALENESULFONATO-.KAPPA.O))(2-)))DIPHENYLDIMERCURY

Common Name

English

PHENYLMERCURIC 3,3'-METHYLENEBIS(2-NAPHTHALENESULPHONATE)

Common Name

English

PHENYLMERCURIC 3,3'-METHYLENEBIS(2-NAPHTHALENESULFONATE)

Common Name

English

.MU.-(2,2'-BINAPHTHALENE-3-SULFONYLOXY)BIS(PHENYLMERCURY)

Common Name

English

HYDRARGAPHEN [MI]

Common Name

English

hydrargaphen [INN]

Common Name

English

HYDRARGAPHEN [MART.]

Common Name

English

Hydrargaphen [WHO-DD]

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

238-107-1