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Details

Stereochemistry ABSOLUTE
Molecular Formula 2C14H23N6O4.Cu
Molecular Weight 742.286
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BISPREZATIDE COPPER

SMILES

[Cu++].NCCCC[C@H](NC(=O)[C@H](CC1=CNC=N1)NC(=O)CN)C([O-])=O.NCCCC[C@H](NC(=O)[C@H](CC2=CNC=N2)NC(=O)CN)C([O-])=O

InChI

InChIKey=YINACRBQQGZRRM-XTQNZXNBSA-L
InChI=1S/2C14H24N6O4.Cu/c2*15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;/h2*7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);/q;;+2/p-2/t2*10-,11-;/m00./s1

HIDE SMILES / InChI

Molecular Formula C14H23N6O4
Molecular Weight 339.3702
Charge -1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula Cu
Molecular Weight 63.546
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Prezatide is a tripeptide molecule consisiting of lysine, glycine and histidine, also known as GHK (glycyl-L-histidyl-L-lysine), that forms a complex with copper ions. Prezatide is used in cosmetic products (skin and hair) and is known help wound healing. Prezatide increases the synthesis and deposition of type I collagen and glycosaminoglycan. It is thought to play a role in the modulation of tissue remodeling by increases the expression of matrix metalloproteinase-2, as well as tissue inhibitor of matrix metalloproteinases-1 and -2. Prezatide has antioxidant activity due to its ability to supply copper for superoxide dismutase and anti-inflammatory ability due to the blockage the of iron (Fe2+) release during injury.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
Volu-Firm

Approved Use

Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:35:54 GMT 2023
Edited
by admin
on Sat Dec 16 08:35:54 GMT 2023
Record UNII
DL1TR6W6VM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BISPREZATIDE COPPER
Common Name English
BIS-PREZATIDE COPPER
Common Name English
GHK BIS COMPLEX WITH COPPER [MI]
Common Name English
CUPRATE(1-), (N2-(GLYCYL-L-HISTIDYL-.KAPPA.N3)-L-LYSINATO)(N2-(GLYCYL-.KAPPA.N-L-HISTIDYL-.KAPPA.N3)-L-LYSINATO(2-))-, HYDROGEN (1:1)
Common Name English
Code System Code Type Description
CAS
130120-56-8
Created by admin on Sat Dec 16 08:35:54 GMT 2023 , Edited by admin on Sat Dec 16 08:35:54 GMT 2023
PRIMARY
PUBCHEM
9831891
Created by admin on Sat Dec 16 08:35:54 GMT 2023 , Edited by admin on Sat Dec 16 08:35:54 GMT 2023
PRIMARY
FDA UNII
DL1TR6W6VM
Created by admin on Sat Dec 16 08:35:54 GMT 2023 , Edited by admin on Sat Dec 16 08:35:54 GMT 2023
PRIMARY
MERCK INDEX
m5722
Created by admin on Sat Dec 16 08:35:54 GMT 2023 , Edited by admin on Sat Dec 16 08:35:54 GMT 2023
PRIMARY Merck Index