GKT-136901

CC1=C2C(=O)N(NC2=CC(=O)N1CC3=CC=CC=N3)C4=CC=CC=C4Cl

InChIKey=DNKYHHFCPXKFIY-UHFFFAOYSA-N

InChI=1S/C19H15ClN4O2/c1-12-18-15(10-17(25)23(12)11-13-6-4-5-9-21-13)22-24(19(18)26)16-8-3-2-7-14(16)20/h2-10,22H,11H2,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
NADPH oxidase 1 6 Target ID: CHEMBL1287628 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27273790	Inhibitor 8297		160.0 nM [Ki]
NADPH oxidase 4 3 Target ID: CHEMBL1250375 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27273790	Inhibitor 8297		165.0 nM [Ki]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:18:56 GMT 2023` Edited by `admin` on `Sat Dec 16 15:18:56 GMT 2023`
Record UNII	DH3KL5M2VQ
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

GKT-136901

Code

English

1H-PYRAZOLO(4,3-C)PYRIDINE-3,6(2H,5H)-DIONE, 2-(2-CHLOROPHENYL)-4-METHYL-5-(2-PYRIDINYLMETHYL)-

Systematic Name

English

2-(2-CHLOROPHENYL)-4-METHYL-5-(PYRIDIN-2-YLMETHYL)-1H-PYRAZOLO(4,3-C)PYRIDINE-3,6-DIONE

Systematic Name

English

2-(2-CHLOROPHENYL)-4-METHYL-5-(2-PYRIDINYLMETHYL)-1H-PYRAZOLO(4,3-C)PYRIDINE-3,6(2H,5H)-DIONE

Systematic Name

English

Code System Code Type Description

PUBCHEM

17027464