AZD-1678

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H8Cl2FN3O3S
Molecular Weight	352.169
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(NS(=O)(=O)C2=C(Cl)C(Cl)=CC=C2)N=CC(F)=N1

InChI

InChIKey=NWSUDJQTTGDPIR-UHFFFAOYSA-N

InChI=1S/C11H8Cl2FN3O3S/c1-20-11-10(15-5-8(14)16-11)17-21(18,19)7-4-2-3-6(12)9(7)13/h2-5H,1H3,(H,15,17)

HIDE SMILES / InChI

Molecular Formula	C11H8Cl2FN3O3S
Molecular Weight	352.169
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Tue Apr 01 16:50:04 GMT 2025` Edited by `admin` on `Tue Apr 01 16:50:04 GMT 2025`
Record UNII	DF5M8SYV7J
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AZD-1678

Code

English

2,3-DICHLORO-N-(5-FLUORO-3-METHOXY-PYRAZIN-2-YL)BENZENESULFONAMIDE

Preferred Name

English

AZD1678

Code

English

2,3-DICHLORO-N-(5-FLUORO-3-METHOXY-2-PYRAZINYL)BENZENESULFONAMIDE

Systematic Name

English

BENZENESULFONAMIDE, 2,3-DICHLORO-N-(5-FLUORO-3-METHOXY-2-PYRAZINYL)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

23585443

Created by admin on Tue Apr 01 16:50:04 GMT 2025 , Edited by admin on Tue Apr 01 16:50:04 GMT 2025

PRIMARY

FDA UNII

DF5M8SYV7J

Created by admin on Tue Apr 01 16:50:04 GMT 2025 , Edited by admin on Tue Apr 01 16:50:04 GMT 2025

PRIMARY

CAS

942137-41-9

Created by admin on Tue Apr 01 16:50:04 GMT 2025 , Edited by admin on Tue Apr 01 16:50:04 GMT 2025

PRIMARY

Related Record Type Details


					DF5M8SYV7J

AZD-1678

ACTIVE MOIETY

Comments:

Originator: AstraZeneca; Class: Pyrazine, Small molecule, Sulfonamide; Mechanism of Action: CCR4 receptor antagonist; Highest Development Phase: Preclinical for Allergic asthma; Most Recent Event: 20 Aug 2009 Preclinical trials in Allergic asthma in United Kingdom (unspecified route)