Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 13:37:56 GMT 2023
by
admin
on
Sat Dec 16 13:37:56 GMT 2023
|
| Protein Type | RECEPTOR |
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
DEI7IFD2OG
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DEI7IFD2OG
Created by
admin on Sat Dec 16 13:37:56 GMT 2023 , Edited by admin on Sat Dec 16 13:37:56 GMT 2023
|
PRIMARY | |||
|
Q9NR61
Created by
admin on Sat Dec 16 13:37:56 GMT 2023 , Edited by admin on Sat Dec 16 13:37:56 GMT 2023
|
PRIMARY |
| From | To |
|---|---|
| 1_24 | 1_28 |
| 1_35 | 1_48 |
| 1_227 | 1_238 |
| 1_233 | 1_244 |
| 1_262 | 1_274 |
| 1_268 | 1_284 |
| 1_286 | 1_295 |
| 1_302 | 1_313 |
| 1_307 | 1_322 |
| 1_324 | 1_333 |
| 1_340 | 1_351 |
| 1_345 | 1_362 |
| 1_364 | 1_373 |
| 1_380 | 1_391 |
| 1_385 | 1_400 |
| 1_402 | 1_411 |
| 1_418 | 1_429 |
| 1_423 | 1_438 |
| 1_440 | 1_449 |
| 1_458 | 1_469 |
| 1_463 | 1_480 |
| 1_482 | 1_491 |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_82 |
| N | 1_157 |
| N | 1_179 |
| N | 1_367 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
INHIBITOR -> TARGET |
Specifically binds to DLL4 and prevents its interaction with Notch receptors, thereby inhibiting Notch-mediated signaling and gene transcription, which may block tumor angiogenesis and eventually the inhibition of tumor cell growth.
|
||
|
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|