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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 01:47:13 GMT 2025
Edited
by admin
on Wed Apr 02 01:47:13 GMT 2025
Protein Type FC FUSION PROTEIN
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
DE9GN7CD21
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Davoceticept
INN   USAN  
Official Name English
ALPN-202
Preferred Name English
1-107-CD80 antigen [18-tyrosine,26-glutamic acid,35-aspartic acid,47-leucine,68-methionine,71-glycine,90-glycine] (human) fusion protein with peptide linker (GSGGGGS) fusion protein with immunoglobulin G1 [119-serine,133-alanine,134-glutamic acid,136-ala
Common Name English
Davoceticept [WHO-DD]
Common Name English
davoceticept [INN]
Common Name English
fragment (1-107) of human T-lymphocyte activation antigen CD80 (CTLA-4 (cytotoxic T-lymphocyte antigen 4) counterreceptor B7.1) variant (H18>Y, A26>E, E35>D, M47>L, V68>M, A71>G, D90>G) fused, via peptidyl linker 108GSGGGGS114 to human immunoglobulin G1
Common Name English
DAVOCETICEPT [USAN]
Common Name English
ALPN202
Code English
Code System Code Type Description
CAS
2307144-64-3
Created by admin on Wed Apr 02 01:47:13 GMT 2025 , Edited by admin on Wed Apr 02 01:47:13 GMT 2025
PRIMARY
NCI_THESAURUS
C174515
Created by admin on Wed Apr 02 01:47:13 GMT 2025 , Edited by admin on Wed Apr 02 01:47:13 GMT 2025
PRIMARY
USAN
KL-165
Created by admin on Wed Apr 02 01:47:13 GMT 2025 , Edited by admin on Wed Apr 02 01:47:13 GMT 2025
PRIMARY
SMS_ID
300000041911
Created by admin on Wed Apr 02 01:47:13 GMT 2025 , Edited by admin on Wed Apr 02 01:47:13 GMT 2025
PRIMARY
FDA UNII
DE9GN7CD21
Created by admin on Wed Apr 02 01:47:13 GMT 2025 , Edited by admin on Wed Apr 02 01:47:13 GMT 2025
PRIMARY
INN
11827
Created by admin on Wed Apr 02 01:47:13 GMT 2025 , Edited by admin on Wed Apr 02 01:47:13 GMT 2025
PRIMARY
From To
1_16 1_82
1_160 1_220
1_266 1_324
2_16 2_82
2_160 2_220
2_266 2_324
1_125 2_125
1_128 2_128
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_19
N 1_55
N 1_64
N 1_196
N 2_19
N 2_55
N 2_64
N 2_196
Related Record Type Details
Davoceticept
ACTIVE MOIETY
ALPN-202 is pharmacologically active in rodents and non-human primates
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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