U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Structurally Diverse
Created
by admin
on Wed Apr 02 07:59:43 GMT 2025
Edited
by admin
on Wed Apr 02 07:59:43 GMT 2025
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE GENETICALLY MODIFIED
Organism Family Retrovirdae
Organism Genus Leukavirus
Organism Species moloney virus
Author NONE
Infraspecific Type SUBSTRAIN
Infraspecific Name MOLONEY MURINE LEUKEMIA VIRUS-IRES-YCD2
Part whole
Record UNII
DC4WO3WA4Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VOCIMAGENE AMIRETROREPVEC
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
vocimagene amiretrorepvec [INN]
Preferred Name English
TOCA-511
Code English
TOCA 511
Code English
VOCIMAGENE AMIRETROREPVEC [USAN]
Common Name English
RECOMBINANT REPLICATION-COMPETENT RETROVIRUS VECTOR ENCODING A HUMAN CODON OPTIMIZED YEAST CYTOSINE DEAMINASE GENE, CARRYING THREE STABILIZING POINT MUTATIONS (A23L/ V108T/I140L) AND TRANSLATED VIA AN EMCV IRES (ENCEPHALOMYOCARDITIS VIRUS INTERNAL RIBOSO
Common Name English
Vocimagene amiretrorepvec [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1962
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
EU-Orphan Drug EU/3/18/1987
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
NCI_THESAURUS C129821
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
NCI_THESAURUS C61199
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
Code System Code Type Description
ChEMBL
CHEMBL2108627
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
PRIMARY
CAS
1300724-82-6
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
PRIMARY
USAN
YY-147
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
PRIMARY
SMS_ID
100000177210
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
PRIMARY
DRUG BANK
DB15331
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
PRIMARY
INN
9603
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
PRIMARY
NCI_THESAURUS
C91734
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
PRIMARY
FDA UNII
DC4WO3WA4Q
Created by admin on Wed Apr 02 07:59:43 GMT 2025 , Edited by admin on Wed Apr 02 07:59:43 GMT 2025
PRIMARY
Related Record Type Details
MOLONEY MURINE LEUKEMIA VIRUS
STARTING MATERIAL -> INGREDIENT
Related Record Type Details
VOCIMAGENE AMIRETROREPVEC
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
INSERTED GENE EXPRESSION VECTOR VOCIMAGENE AMIRETROREPVEC TRANSGENE INSERT O5R27129Y3
NIH
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