Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C26H29FN2O2 |
| Molecular Weight | 420.5191 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
FC1=CC=C(CN2CCC(CCC(=O)C3=CC4=C5N(CCC5=C3)C(=O)CC4)CC2)C=C1
InChI
InChIKey=SJUJPEIDAFVFPE-UHFFFAOYSA-N
InChI=1S/C26H29FN2O2/c27-23-5-1-19(2-6-23)17-28-12-9-18(10-13-28)3-7-24(30)22-15-20-4-8-25(31)29-14-11-21(16-22)26(20)29/h1-2,5-6,15-16,18H,3-4,7-14,17H2
| Molecular Formula | C26H29FN2O2 |
| Molecular Weight | 420.5191 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Differential effects of TAK-802, a selective acetylcholinesterase inhibitor, and carbamate acetylcholinesterase inhibitors on contraction of the detrusor smooth muscle of the guinea pig. | 2005-11-12 |
|
| Effects of the selective acetylcholinesterase inhibitor TAK-802 on the voiding behavior and bladder mass increase in rats with partial bladder outlet obstruction. | 2005-09 |
|
| Effects of TAK-802, a novel acetylcholinesterase inhibitor, and tamsulosin, an alpha1-adrenoceptor antagonist, and their synergistic effects on the urodynamic characteristics in a guinea-pig model of functional bladder outlet obstruction. | 2005-05 |
|
| Novel acetylcholinesterase inhibitor as increasing agent on rhythmic bladder contractions: SAR of 8-{3-[1-(3-fluorobenzyl)piperidin-4-yl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one (TAK-802) and related compounds. | 2005-03-15 |
|
| Effects of TAK-802, a novel acetylcholinesterase inhibitor, and various cholinomimetics on the urodynamic characteristics in anesthetized guinea pigs. | 2004-06-28 |
|
| Effects of TAK-802, a novel acetylcholinesterase inhibitor, on distension-induced rhythmic bladder contractions in rats and guinea pigs. | 2004-02-06 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:12:00 GMT 2025
by
admin
on
Mon Mar 31 18:12:00 GMT 2025
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| Record UNII |
D91A4HRG9Y
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| Record Status |
Validated (UNII)
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| Record Version |
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131842169
Created by
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D91A4HRG9Y
Created by
admin on Mon Mar 31 18:12:00 GMT 2025 , Edited by admin on Mon Mar 31 18:12:00 GMT 2025
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850007-48-6
Created by
admin on Mon Mar 31 18:12:00 GMT 2025 , Edited by admin on Mon Mar 31 18:12:00 GMT 2025
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PRIMARY |
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