U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Jun 26 16:57:30 UTC 2021
Edited
by admin
on Sat Jun 26 16:57:30 UTC 2021
Source Materials Class ORGANISM
Source Materials Type PLANT
Source Materials Parent
Part SEED
Fraction Name ROASTED
Record UNII
D9108TZ9KG
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
COCOA
MI   VANDF  
Common Name English
THEOBROMA CACAO SEED [WHO-DD]
Common Name English
CACAO (COCOA) [FHFI]
Common Name English
COCOA [VANDF]
Common Name English
THEOBROMA CACAO SEED
WHO-DD  
Common Name English
COCOA POWDER
Common Name English
COCOA [MI]
Common Name English
CHOCOLATE
Common Name English
CHOCOLATE SEED, FERMENTED
Common Name English
CACAO SEED, FERMENTED
Common Name English
THEOBROMA CACAO SEED, FERMENTED
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C62695
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
DSLD 704 (Number of products:337)
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
NDF-RT N0000185371
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
DSLD 3008 (Number of products:4)
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
Code System Code Type Description
NCI_THESAURUS
C121851
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY NCIT
EVMPD
SUB88720
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY
NDF-RT
N0000171131
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY Allergens [Chemical/Ingredient]
NDF-RT
N0000008246
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY Plant Proteins [Chemical/Ingredient]
NDF-RT
N0000007512
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY Dietary Proteins [Chemical/Ingredient]
NDF-RT
N0000184306
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY Cell-mediated Immunity [PE]
ChEMBL
CHEMBL2108233
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY
FDA UNII
D9108TZ9KG
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY
ChEMBL
CHEMBL2108921
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY
MERCK INDEX
M3715
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY Merck Index
DRUG BANK
DB10977
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY
LACTMED
Chocolate
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY
EVMPD
SUB70260
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY
NDF-RT
N0000175629
Created by admin on Sat Jun 26 16:57:33 UTC 2021 , Edited by admin on Sat Jun 26 16:57:33 UTC 2021
PRIMARY Increased Histamine Release [PE]
Related Record Type Details
SUB_CONCEPT->SUBSTANCE
CONSTITUENT ALWAYS PRESENT -> PARENT
83+-2% Mean adhesion, related to the untreated control) of FITC-labeled H. pylori to AGS cells after 2 h pretreatment with different NPAs (2mM)
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
SUB_CONCEPT->SUBSTANCE
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
CONSTITUENT ALWAYS PRESENT -> PARENT
119+-21% Mean adhesion, related to the untreated control) of FITC-labeled H. pylori to AGS cells after 2 h pretreatment with different NPAs (2mM)
CONSTITUENT ALWAYS PRESENT -> PARENT
To determine the influence of the antiadhesive BabA blocker 11 on the gene expression of bacterial adhesins and virulence factors and especially on a potential correlation of adhesion with expression of virulence factors, H. pylori was incubated with N-(E)-caffeoyl-L-glutamic acid amide 11 and with inactive N-(E)-feruoyl-L-tyrosine amide. Pretreatment of H. pylori with the non-antiadhesive compound did not induce substantial difference in expression of the studied virulence factors.
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
CONSTITUENT ALWAYS PRESENT -> PARENT
78+-13% Mean adhesion, related to the untreated control) of FITC-labeled H. pylori to AGS cells after 2 h pretreatment with different NPAs (2mM)
SUB_CONCEPT->SUBSTANCE
CONSTITUENT ALWAYS PRESENT -> PARENT
88+-4% Mean adhesion, related to the untreated control) of FITC-labeled H. pylori to AGS cells after 2 h pretreatment with different NPAs (2mM)
SUB_CONCEPT->SUBSTANCE
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
CONSTITUENT ALWAYS PRESENT -> PARENT
103+-12% Mean adhesion, related to the untreated control) of FITC-labeled H. pylori to AGS cells after 2 h pretreatment with different NPAs (2mM)
CONSTITUENT ALWAYS PRESENT -> PARENT
Tests on human gastric tissues and evaluation of the binding of FITC-labeled H. pylori by fluorescence imaging confirmed the results from the flowcytometric assay in vitro assay showed this compound to be inactive.
CONSTITUENT ALWAYS PRESENT -> PARENT
82+-9 % Mean adhesion, related to the untreated control) of FITC-labeled H. pylori to AGS cells after 2 h pretreatment with different NPAs (2mM)
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
SUB_CONCEPT->SUBSTANCE
CONSTITUENT ALWAYS PRESENT -> PARENT
a hyroxycinnamic acid amide
CONSTITUENT ALWAYS PRESENT -> PARENT
85+-7 % Mean adhesion, related to the untreated control) of FITC-labeled H. pylori to AGS cells after 2 h pretreatment with different NPAs (2mM)
ACTIVE CONSTITUENT ALWAYS PRESENT -> PARENT
93+-10% Mean adhesion, related to the untreated control) of FITC-labeled H. pylori to AGS cells after 2 h pretreatment with different NPAs (2mM)
CONSTITUENT ALWAYS PRESENT -> PARENT
Secondary metabolite detected in developing cacao seeds.
CONSTITUENT ALWAYS PRESENT -> PARENT
91+-4% Mean adhesion, related to the untreated control) of FITC-labeled H. pylori to AGS cells after 2 h pretreatment with different NPAs (2mM)
Related Record Type Details
ACTIVE MOIETY