U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C10H5ClN2
Molecular Weight 188.613
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of O-CHLOROBENZYLIDENEMALONONITRILE

SMILES

ClC1=CC=CC=C1C=C(C#N)C#N

InChI

InChIKey=JJNZXLAFIPKXIG-UHFFFAOYSA-N
InChI=1S/C10H5ClN2/c11-10-4-2-1-3-9(10)5-8(6-12)7-13/h1-5H

HIDE SMILES / InChI

Molecular Formula C10H5ClN2
Molecular Weight 188.613
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Educating on CS or 'tear gas'.
2010-11
A study for health hazard evaluation of methylene chloride evaporated from the tear gas mixture.
2010-09
Identification of compounds formed during low temperature thermal dispersion of encapsulated o-chlorobenzylidene malononitrile (CS riot control agent).
2010-06
Lesions in the Larynx of Wistar RccHan: WIST Rats.
2009-12
Acute laryngeal and bronchial obstruction after CS (o-chlorobenzylidenemalononitrile) gas inhalation.
2009-02
2-Amino-4-(2-chloro-phen-yl)-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromene-3-carbonitrile.
2008-12-03
Tear gasses CN, CR, and CS are potent activators of the human TRPA1 receptor.
2008-09-01
Investigation of accidental secondary exposure to CS agent.
2007-05
Analysis of trace amount of bank dye and lachrymators from exploding bank devices by solid-phase microextraction and gas chromatography-mass spectrometry.
2006-02
Medical management of the traumatic consequences of civil unrest incidents: causation, clinical approaches, needs and advanced planning criteria.
2006
Unintended cutaneous reactions to CS spray.
2005-07
Secondary contamination of emergency department personnel from o-chlorobenzylidene malononitrile exposure, 2002.
2005-06
Tear gases and irritant incapacitants. 1-chloroacetophenone, 2-chlorobenzylidene malononitrile and dibenz[b,f]-1,4-oxazepine.
2003
Liberation of hydrogen cyanide and hydrogen chloride during high-temperature dispersion of CS riot control agent.
2002-12-19
An evaluation of the relative potential public health concern for the self-defense spray active ingredients oleoresin capsicum, o-chlorobenzylidene malononitrile, and 2-chloroacetophenone.
2002-08
Formation of 2-chlorobenzylidenemalononitrile (CS riot control agent) thermal degradation products at elevated temperatures.
2002-04-05
Riot control agents: pharmacology, toxicology, biochemistry and chemistry.
2001-12-18
Effect of oleoresin capsicum (OC) and ortho-chlorobenzylidene malononitrile (CS) on ciliary beat frequency.
2001-08-28
An assessment of four solvents for the recovery of 2-chlorobenzylidenemalononitrile and capsaicins from "CS" and "Pepper" type lachrymator sprays, and an examination of their persistence on cotton fabric.
2001-03
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:27:10 GMT 2025
Edited
by admin
on Mon Mar 31 19:27:10 GMT 2025
Record UNII
D8317IAV7Q
Record Status Validated (UNII)
Record Version
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Name Type Language
O-CHLOROBENZYLIDENEMALONONITRILE
MI  
Common Name English
NCI-C55118
Preferred Name English
PROPANEDINITRILE, ((2-CHLOROPHENYL)METHYLENE)-
Systematic Name English
CHLOROBENZALMALONITRILE, O-
Systematic Name English
O-CHLOROBENZYLIDENE MALONONITRILE
Common Name English
O-CHLOROBENZALMALONONITRILE
Common Name English
2-((2-CHLOROPHENYL)METHYLENE)PROPANEDINITRILE
Systematic Name English
2-CHLOROBENZALMALONONITRILE [HSDB]
Common Name English
NSC-542
Code English
.BETA.,.BETA.-DICYANO-O-CHLOROSTYRENE
Common Name English
O-CHLOROBENZYLIDENEMALONONITRILE [MI]
Common Name English
2-CHLOROBENZYLIDENEMALONONITRILE
Systematic Name English
Code System Code Type Description
CAS
2698-41-1
Created by admin on Mon Mar 31 19:27:10 GMT 2025 , Edited by admin on Mon Mar 31 19:27:10 GMT 2025
PRIMARY
EPA CompTox
DTXSID9020297
Created by admin on Mon Mar 31 19:27:10 GMT 2025 , Edited by admin on Mon Mar 31 19:27:10 GMT 2025
PRIMARY
WIKIPEDIA
CS gas
Created by admin on Mon Mar 31 19:27:10 GMT 2025 , Edited by admin on Mon Mar 31 19:27:10 GMT 2025
PRIMARY
NSC
542
Created by admin on Mon Mar 31 19:27:10 GMT 2025 , Edited by admin on Mon Mar 31 19:27:10 GMT 2025
PRIMARY
MERCK INDEX
m3398
Created by admin on Mon Mar 31 19:27:10 GMT 2025 , Edited by admin on Mon Mar 31 19:27:10 GMT 2025
PRIMARY Merck Index
FDA UNII
D8317IAV7Q
Created by admin on Mon Mar 31 19:27:10 GMT 2025 , Edited by admin on Mon Mar 31 19:27:10 GMT 2025
PRIMARY
HSDB
4346
Created by admin on Mon Mar 31 19:27:10 GMT 2025 , Edited by admin on Mon Mar 31 19:27:10 GMT 2025
PRIMARY
PUBCHEM
17604
Created by admin on Mon Mar 31 19:27:10 GMT 2025 , Edited by admin on Mon Mar 31 19:27:10 GMT 2025
PRIMARY
ECHA (EC/EINECS)
220-278-9
Created by admin on Mon Mar 31 19:27:10 GMT 2025 , Edited by admin on Mon Mar 31 19:27:10 GMT 2025
PRIMARY