U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C6H18OSi2
Molecular Weight 162.3775
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Hexamethyldisiloxane

SMILES

C[Si](C)(C)O[Si](C)(C)C

InChI

InChIKey=UQEAIHBTYFGYIE-UHFFFAOYSA-N
InChI=1S/C6H18OSi2/c1-8(2,3)7-9(4,5)6/h1-6H3

HIDE SMILES / InChI

Molecular Formula C6H18OSi2
Molecular Weight 162.3775
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Effects of surface properties of different substrates on fine structure of plasma-polymerized SiOCH films prepared from hexamethyldisiloxane (HMDSO).
2010-11-16
Interface roughness of plasma deposited polymer layers.
2010-11-15
Enzyme mediated silicon-oxygen bond formation; the use of Rhizopus oryzae lipase, lysozyme and phytase under mild conditions.
2010-10-21
In vitro biocompatibility of plasma-aided surface-modified 316L stainless steel for intracoronary stents.
2010-10
Effect of titanium oxide nanoparticle incorporation into nm thick coatings deposited using an atmospheric pressure plasma.
2010-04
Hybrid layers deposited by an atmospheric pressure plasma process for corrosion protection of galvanized steel.
2010-04
Surface water concentrations and loading budgets of pharmaceuticals and other domestic-use chemicals in an urban watershed (Washington, DC, USA).
2010-04
Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C.
2010-01-21
Quantitative analysis of volatile methylsiloxanes in waste-to-energy landfill biogases using direct APCI-MS/MS.
2010-01-15
Anti-fogging nanofibrous SiO(2) and nanostructured SiO(2)-TiO(2) films made by rapid flame deposition and in situ annealing.
2009-11-03
Plasma surface modification of cyclo-olefin polymers and its application to lateral flow bioassays.
2009-09-15
Siloxane treatment by adsorption into porous materials.
2009-09
Influence of surface wettability on competitive protein adsorption and initial attachment of osteoblasts.
2009-08
Rapid characterization of agglomerate aerosols by in situ mass-mobility measurements.
2009-07-21
Asymmetric allylation of methyl ketones by using chiral phenyl carbinols.
2009-06-15
Quantitative analysis of ezetimibe in human plasma by gas chromatography-mass spectrometry.
2009-06
Blue nano titania made in diffusion flames.
2009-05-21
The domino multicomponent allylation reaction for the stereoselective synthesis of homoallylic alcohols.
2009-02-17
Enantioselective cyanosilylation of ketones catalyzed by recyclable polymeric and dimeric Mn(III) salen complexes at room temperature.
2009-02
Fluoride intake from meals served in daycare centres in municipalities with different fluoride concentrations in the water supply.
2009
The potential of nano-structured silicon oxide type coatings deposited by PACVD for control of aquatic biofouling.
2009
In situ coating of flame-made TiO2 particles with nanothin SiO2 films.
2008-11-04
One-pot conversion of trimethylsilyl ethers into urethanes using chlorosulfonyl isocyanate: application to the synthesis of a novel neuromodulator carisbamate.
2008-11
Evolution of the surface polar character of pyrogenic silicas, with their grafting ratios by dimethylchlorosilane, studied by microcalorimetry.
2008-09-01
Analysis of chemically synthesized oleoylethanolamide by gas-liquid chromatography.
2008-08-22
Plasma-enhanced synthesis of bactericidal quaternary ammonium thin layers on stainless steel and cellulose surfaces.
2008-08-19
Plasma treatments of PET meshes for fuel-water separation applications.
2008-06-15
Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry.
2008-03-25
Metal-dependent reactions of bulky metal(II) amides M[N(SiMe3)2]2 with 3,3'-disubstituted binaphthols (HO)2C20H10(SiR3)2-3,3': selective conversion of one equivalent -OH group to a silyl ether -OSiMe3.
2008-03-17
Particle morphology of various SiC-based nanocomposite powders made by the aerosol-assisted synthesis method.
2008-02
Free and conjugated phytosterols in cured tobacco leaves: influence of genotype, growing region, and stalk position.
2008-01-09
Physical principles of quantitative nuclear magnetic resonance oximetry.
2008-01-01
InCl3/I2-catalyzed cross-coupling of alkyl trimethylsilyl ethers and allylsilanes via an in situ derived combined Lewis acid of InCl3 and Me3SiI.
2007-10-26
Electron and ion reactions with hexamethyldisiloxane and pentamethyldisiloxane.
2007-10-14
Analysis of free and conjugated phytosterols in tobacco by an improved method using gas chromatography-flame ionization detection.
2007-09-07
Intermolecular C-H bond activation reactions promoted by transient titanium alkylidynes. Synthesis, reactivity, kinetic, and theoretical studies of the Ti[triple bond]C linkage.
2007-07-18
Seasonal and geographical variations of sterol composition in snow crab hepatopancreas and pelagic fish viscera from Eastern Quebec.
2007-07
Don't be so BOLD: potential limitations in the use of BOLD MRI for studies of renal oxygenation.
2007-06
Adhesion of mouse fibroblasts on hexamethyldisiloxane surfaces with wide range of wettability.
2007-04
Encapsulation of a highly sensitive EPR active oxygen probe into sonochemically prepared microspheres.
2007-03-29
Vibrational spectroscopic analysis of chlorosilanes and siloxane oligomers: implications for the spectra of polydimethylsiloxanes.
2007-03
Organosilicon-containing thiazole derivatives as potential lipoxygenase inhibitors and anti-inflammatory agents.
2007
Sterol composition in muscle and viscera of the marine bivalve Megangulus zyonoensis from coastal waters of Hokkaido, northern Japan.
2007
Adsorption of glucose oxidase onto plasma-polymerized film characterized by atomic force microscopy, quartz crystal microbalance, and electrochemical measurement.
2006-12-28
Porogen approach for the fabrication of plasma-polymerized nanoporous polysiloxane films.
2006-10-19
Adsorption of human salivary mucin MG1 onto glow-discharge plasma treated acrylic resin surfaces.
2006-10
Modified chemistry of siloxanes under tensile stress: interaction with environment.
2006-08-03
Bond strength of a composite luting agent to alumina ceramic surfaces.
2006-08
Analysis of fluoride concentration in mother's milk substitutes.
2005-10-14
Characterization of diffusion-controlled mass transport through nanoporous and nanothin films plasma polymerized on a sputtered platinum electrode.
2005-10-13
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:45:00 GMT 2025
Edited
by admin
on Mon Mar 31 18:45:00 GMT 2025
Record UNII
D7M4659BPU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Hexamethyldisiloxane
HSDB   MI   VANDF  
Systematic Name English
DISILOXANE
INCI  
INCI  
Preferred Name English
VOLASIL DM-0.65
Brand Name English
SI-TEC DM 0.65
Brand Name English
DOW CORNING 200
Brand Name English
HEXAMETHYLDISILOXANE [HSDB]
Common Name English
XIAMETER(R) PMX-200 SILICONE FLUID 0.65 CST
Brand Name English
BELSIL DM 0.65
Brand Name English
HEXAMETHYLDISILOXANE [VANDF]
Common Name English
AEC DISILOXANE
Brand Name English
HEXAMETHYLDISILOXANE [MI]
Common Name English
OXYBIS(TRIMETHYLSILANE)
Systematic Name English
DISILOXANE, HEXAMETHYL-
Systematic Name English
NSC-43346
Code English
MIRASIL HMS
Brand Name English
BIS(TRIMETHYLSILYL)ETHER
Systematic Name English
SF1000N-0.65CST
Brand Name English
Code System Code Type Description
ECHA (EC/EINECS)
203-492-7
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
CHEBI
85068
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
EVMPD
SUB185133
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
CAS
107-46-0
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
NSC
43346
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
CHEBI
78002
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
PUBCHEM
24764
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
NCI_THESAURUS
C92605
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
SMS_ID
100000160938
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
HSDB
5378
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
DAILYMED
D7M4659BPU
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
FDA UNII
D7M4659BPU
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
CHEBI
48141
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
MERCK INDEX
m5996
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY Merck Index
EVMPD
SUB174008
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
EPA CompTox
DTXSID4026769
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
CONCEPT Industrial Aid
WIKIPEDIA
HEXAMETHYLDISILOXANE
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY
RXCUI
1311540
Created by admin on Mon Mar 31 18:45:00 GMT 2025 , Edited by admin on Mon Mar 31 18:45:00 GMT 2025
PRIMARY RxNorm