TRICLOBISONIUM

US Previously Marketed

First approved in 1959

Details

Stereochemistry	MIXED
Molecular Formula	C36H74N2
Molecular Weight	534.9862
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 6
E/Z Centers	0
Charge	2

SHOW SMILES / InChI

Structure Search

SMILES

CC(CCC1C(C)CCCC1(C)C)[N+](C)(C)CCCCCC[N+](C)(C)C(C)CCC2C(C)CCCC2(C)C

InChI

InChIKey=YECRYLBCIYSJSO-UHFFFAOYSA-N

InChI=1S/C36H74N2/c1-29-19-17-25-35(5,6)33(29)23-21-31(3)37(9,10)27-15-13-14-16-28-38(11,12)32(4)22-24-34-30(2)20-18-26-36(34,7)8/h29-34H,13-28H2,1-12H3/q+2

HIDE SMILES / InChI

Molecular Formula	C36H74N2
Molecular Weight	534.9862
Charge	2
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13819270 | https://www.ncbi.nlm.nih.gov/pubmed/13800549

TRICLOBISONIUM (as a chloride salt) is an antibacterial agent used for the treatment and/or prevention of local infections.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Trichomonas vaginalis 2 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13726669	Primary		Approved 8429	Triburon Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
ABI Chem	AC1L1MX4
Alfa Chemistry	ACM79903
ZINC	ZINC000003875528	http://zinc15.docking.org/substances/ZINC000003875528
ZINC	ZINC000003875529	http://zinc15.docking.org/substances/ZINC000003875529
ZINC	ZINC000003875530	http://zinc15.docking.org/substances/ZINC000003875530
ZINC	ZINC000003875531	http://zinc15.docking.org/substances/ZINC000003875531
eMolecules	260195778

PubMed

Title	Date	PubMed
Local application of triclobisonium chloride in the treatment of pyogenic dermatoses.	1958-1959	13637717
Triclobisonium chloride (triburon), an antimicrobial agent with local activity in living host tissues.	1959 May	24545208
Clinical studies of the effectiveness of a new topical antimicrobial, triclobisonium chloride.	1959 Sep 1	13819270
Trichomonas vaginalis. A clinical evaluation of triclobisonium chloride vaginal cream (Triburon).	1960 Dec	13726669

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:34:44 GMT 2023` Edited by `admin` on `Sat Dec 16 08:34:44 GMT 2023`
Record UNII	D75WGE9M1B
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRICLOBISONIUM

Common Name

English

1,6-HEXANEDIAMINIUM, N,N,N',N'-TETRAMETHYL-N,N'-BIS(1-METHYL-3-(2,2,6-TRIMETHYLCYCLOHEXYL)PROPYL)-

Systematic Name

English

TRICLOBISONIUM ION

Common Name

English

1,6-HEXANEDIAMINIUM, N1,N1,N6,N6-TETRAMETHYL-N1,N6-BIS(1-METHYL-3-(2,2,6-TRIMETHYLCYCLOHEXYL)PROPYL)-

Systematic Name

English

TRICLOBISONIUM CATION

Common Name

English

Triclobisonium [WHO-DD]

Common Name

English

Code System Code Type Description

SMS_ID

100000084642