TOFENACIN, (+)-

Possibly Marketed Outside US

Details

Stereochemistry	UNKNOWN
Molecular Formula	C17H21NO
Molecular Weight	255.3547
Optical Activity	( + )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNCCOC(C1=CC=CC=C1)C2=CC=CC=C2C

InChI

InChIKey=PNYKGCPSFKLFKA-UHFFFAOYSA-N

InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)17(19-13-12-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C17H21NO
Molecular Weight	255.3547
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://patents.google.com/patent/WO2010099745A1/it

1-[3-(Benzyloxy)phenyl]-N,N-dimethylethanamine is an intermediate compound in the chemical synthesis of a drug Rivastigmine, which is used to treat Alzheimer's and Parkinson's disease.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Muscarinic acetylcholine receptor 162 Target ID: CHEMBL2094109 Sources: https://www.kegg.jp/entry/D06175\|http://drugcentral.org/drugcard/2692\|https://patents.justia.com/patent/9446030	Antagonist 2849

PubMed

Title	Date	PubMed
A comparative trial of orphenadrine and tofenacin in the control of depression and extrapyramidal side-effects associated with fluphenazine decanoate therapy.	1976	800383

Substance Class	Chemical Created by `admin` on `Tue Apr 01 17:10:25 GMT 2025` Edited by `admin` on `Tue Apr 01 17:10:25 GMT 2025`
Record UNII	D67B6M43WW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ETHYLAMINE, N-METHYL-2-((O-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-, (+)-

Preferred Name

English

TOFENACIN, (+)-

Common Name

English

Code System Code Type Description

FDA UNII

D67B6M43WW

Created by admin on Tue Apr 01 17:10:25 GMT 2025 , Edited by admin on Tue Apr 01 17:10:25 GMT 2025

PRIMARY

CAS

33431-05-9