U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
Crilvastatin is an inhibitor of hydroxymethylglutaryl-coenzyme A reductase. In a rat model, the drug was demonstrated to increase low-density lipoprotein (LDL)-cholesterol uptake by the liver more than high-density lipoprotein uptake, thus increasing the clearance of excess plasma cholesterol.

Approval Year

Substance Class Mixture
Created
by admin
on Fri Dec 15 17:17:16 GMT 2023
Edited
by admin
on Fri Dec 15 17:17:16 GMT 2023
Record UNII
D2B8XWK36K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CRILVASTATIN
INN   USAN  
INN   USAN  
Official Name English
crilvastatin [INN]
Common Name English
5-OXO-L-PROLINE, (±)-CIS-3,3,5-TRIMETHYLCYCLOHEXYL ESTER
Common Name English
L-PROLINE, 5-OXO-, 3,3,5-TRIMETHYLCYCLOHEXYL ESTER
Common Name English
CRILVASTATIN [USAN]
Common Name English
PMD-387
Code English
PMD387
Code English
Classification Tree Code System Code
NCI_THESAURUS C1655
Created by admin on Fri Dec 15 17:17:16 GMT 2023 , Edited by admin on Fri Dec 15 17:17:16 GMT 2023
Code System Code Type Description
CAS
120551-59-9
Created by admin on Fri Dec 15 17:17:16 GMT 2023 , Edited by admin on Fri Dec 15 17:17:16 GMT 2023
PRIMARY
NCI_THESAURUS
C90865
Created by admin on Fri Dec 15 17:17:16 GMT 2023 , Edited by admin on Fri Dec 15 17:17:16 GMT 2023
PRIMARY
FDA UNII
D2B8XWK36K
Created by admin on Fri Dec 15 17:17:16 GMT 2023 , Edited by admin on Fri Dec 15 17:17:16 GMT 2023
PRIMARY
USAN
EE-4
Created by admin on Fri Dec 15 17:17:16 GMT 2023 , Edited by admin on Fri Dec 15 17:17:16 GMT 2023
PRIMARY
EPA CompTox
DTXSID101009438
Created by admin on Fri Dec 15 17:17:16 GMT 2023 , Edited by admin on Fri Dec 15 17:17:16 GMT 2023
PRIMARY
EVMPD
SUB06819MIG
Created by admin on Fri Dec 15 17:17:16 GMT 2023 , Edited by admin on Fri Dec 15 17:17:16 GMT 2023
PRIMARY
INN
6623
Created by admin on Fri Dec 15 17:17:16 GMT 2023 , Edited by admin on Fri Dec 15 17:17:16 GMT 2023
PRIMARY
ChEMBL
CHEMBL2218880
Created by admin on Fri Dec 15 17:17:16 GMT 2023 , Edited by admin on Fri Dec 15 17:17:16 GMT 2023
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Definition References