Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H3FN2O4 |
| Molecular Weight | 186.0974 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[O-][N+](=O)C1=CC(=C(F)C=C1)[N+]([O-])=O
InChI
InChIKey=LOTKRQAVGJMPNV-UHFFFAOYSA-N
InChI=1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H
| Molecular Formula | C6H3FN2O4 |
| Molecular Weight | 186.0974 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| 5-Hydroxytryptamine (5-HT)2 receptor involvement in acute 5-HT-evoked scratching but not in allergic pruritus induced by dinitrofluorobenzene in rats. | 2003-07 |
|
| Protective effect of creatine against inhibition by methylglyoxal of mitochondrial respiration of cardiac cells. | 2003-06-01 |
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| Acute stress modulates the irritant component of sensitizers in allergic contact dermatitis: implications for exposure assessment. | 2003-04-01 |
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| Modulation of cutaneous inflammation by angiotensin-converting enzyme. | 2003-04-01 |
|
| Inhibition of the elicitation phase of contact hypersensitivity by thymidine dinucleotides is in part mediated by increased expression of interleukin-10 in human keratinocytes. | 2003-04 |
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| Divergence of contact hypersensitivity in vivo compared with hapten-specific lymphocyte proliferation and interferon-gamma production in vitro following ultraviolet B irradiation: the possibility that UVB does not affect the sensitizing phase of contact hypersensitivity. | 2003-04 |
|
| Spectrophotometric and polarographic determination of enalapril and lisinopril using 2,4-dinitrofluorobenzene. | 2003-03-26 |
|
| Assessment of glycosylation-dependent cell adhesion molecule 1 as a correlate of allergen-stimulated lymph node activation. | 2003-03-14 |
|
| IL-13 is necessary, not simply sufficient, for epicutaneously induced Th2 responses to soluble protein antigen. | 2003-03-01 |
|
| Restraint stress and corticotropin releasing hormone modulation of murine cutaneous POMC mRNA. | 2003-03 |
|
| The sensitizer 2,4-dinitrofluorobenzene activates caspase-3 and induces cell death in a skin dendritic cell line. | 2003-02-08 |
|
| Identification and quantification of in vitro adduct formation between protein reactive xenobiotics and a lysine-containing model peptide. | 2003-02 |
|
| Effect of Ginkgo biloba extract, EGb 761, on the cellular immune response in a hypothalamic-pituitary-adrenal axis activation model in the rat. | 2003-01 |
|
| Rapid method for the determination of amino acids in serum by capillary electrophoresis. | 2002-12-06 |
|
| Differential activation of nuclear factor kappa B subunits in a skin dendritic cell line in response to the strong sensitizer 2,4-dinitrofluorobenzene. | 2002-12 |
|
| Flare-up reaction on murine contact hypersensitivity. III. Effect of staphylococcal enterotoxin B. | 2002-12 |
|
| Treatment of silymarin, a plant flavonoid, prevents ultraviolet light-induced immune suppression and oxidative stress in mouse skin. | 2002-12 |
|
| Therapeutic potential of a specific chymase inhibitor in atopic dermatitis. | 2002-11 |
|
| Initial recruitment of interferon-gamma-producing CD8+ effector cells, followed by infiltration of CD4+ cells in 2,4,6-trinitro-1-chlorobenzene (TNCB)-induced murine contact hypersensitivity reactions. | 2002-11 |
|
| Anti-inflammatory and anti-allergic activities of hydroxylamine and related compounds. | 2002-11 |
|
| Examination of a vehicle for use with water soluble materials in the murine local lymph node assay. | 2002-11 |
|
| Dinitrophenol derivatization of proteolytic products and its application in the assay of protease(s) activity. | 2002-10-30 |
|
| Essential role of p38 mitogen-activated protein kinase in contact hypersensitivity. | 2002-10-04 |
|
| Different photoperiods affect proliferation of lymphocytes but not expression of cellular, humoral, or innate immunity in hamsters. | 2002-10 |
|
| Low dose of resveratrol enhanced immune response of mice. | 2002-10 |
|
| Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. | 2002-09 |
|
| Role of CD44 in activation-induced cell death: CD44-deficient mice exhibit enhanced T cell response to conventional and superantigens. | 2002-09 |
|
| Hepatic leukocyte recruitment in a model of acute colitis. | 2002-09 |
|
| Sodium metasilicate hypersensitivity in BALB/c mice. | 2002-09 |
|
| Key role for mast cells in nonatopic asthma. | 2002-08-15 |
|
| Elucidating changes in surface marker expression of dendritic cells following chemical allergen treatment. | 2002-08-01 |
|
| Effect of the dose and composition of an autologous hapten-modified melanoma vaccine on the development of delayed-type hypersensitivity responses. | 2002-08 |
|
| Spectrophotometric determination of lisinopril in tablets using 1-fluoro-2,4-dinitrobenzene reagent. | 2002-07-31 |
|
| Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation. | 2002-07 |
|
| Evaluation and characterization of mouse scratching behavior by a new apparatus, MicroAct. | 2002-06-06 |
|
| Phagnalon rupestre as a source of compounds active on contact hypersensitivity. | 2002-06 |
|
| Anti-allergic effects of cnidii monnieri fructus (dried fruits of Cnidium monnieri) and its major component, osthol. | 2002-06 |
|
| Chymase participates in chronic dermatitis by inducing eosinophil infiltration. | 2002-06 |
|
| Effect of cyclosporine in a murine model of experimental colitis. | 2002-06 |
|
| Mast cell-derived TNF-alpha primes sensory nerve endings in a pulmonary hypersensitivity reaction. | 2002-05-15 |
|
| Rigid tetranitroresorcinarenes. | 2002-05-02 |
|
| Comparative study of two Ginkgo biloba extracts on the phagocytic activity and DTH response of healthy mice. | 2002-05 |
|
| Effect of zinc supplementation on intestinal permeability in experimental colitis. | 2002-05 |
|
| Low-dose dithranol treatment and tape stripping induce tolerance to dithranol in a mouse ear oedema model. | 2002-05 |
|
| Dominant expression of CXCR3 is associated with induced expression of IP-10 at hapten-challenged sites of murine contact hypersensitivity: a possible role for interferon-gamma-producing CD8(+) T cells in IP-10 expression. | 2002-04 |
|
| Skin inflammation during contact hypersensitivity is mediated by early recruitment of CD8+ T cytotoxic 1 cells inducing keratinocyte apoptosis. | 2002-03-15 |
|
| Intracellular ATP measured with luciferin/luciferase in isolated single mouse skeletal muscle fibres. | 2002-03 |
|
| Hypersensitivity reactions in mouse airways after a single and a repeated hapten challenge. | 2002-02 |
|
| The Th2-restricted immune response to xenogeneic small intestinal submucosa does not influence systemic protective immunity to viral and bacterial pathogens. | 2002-02 |
|
| Induction and regulation of T-cell priming for contact hypersensitivity. | 2001 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 17:48:44 GMT 2025
by
admin
on
Mon Mar 31 17:48:44 GMT 2025
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| Record UNII |
D241E059U6
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C1915
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NCI_THESAURUS |
C802
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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53049
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33519
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70-34-8
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DTXSID8025331
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m5474
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PRIMARY | Merck Index | ||
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C440
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200-734-3
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6264
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4342
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D004139
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D241E059U6
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1-FLUORO-2,4-DINITROBENZENE
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admin on Mon Mar 31 17:48:44 GMT 2025 , Edited by admin on Mon Mar 31 17:48:44 GMT 2025
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PRIMARY |