Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H12N2O4 |
| Molecular Weight | 344.3203 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=C2C=CC=CC2=NC(=C1)C3=CC(C(O)=O)=C4C=CC=CC4=N3
InChI
InChIKey=AFYNADDZULBEJA-UHFFFAOYSA-N
InChI=1S/C20H12N2O4/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18/h1-10H,(H,23,24)(H,25,26)
| Molecular Formula | C20H12N2O4 |
| Molecular Weight | 344.3203 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo. | 2006-05-18 |
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| Does the nanometre scale topography of titanium influence protein adsorption and cell proliferation? | 2006-05-01 |
|
| Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest. | 2006-04-26 |
|
| Protein rejecting properties of PEG-grafted nanoparticles: influence of PEG-chain length and surface density evaluated by two-dimensional electrophoresis and bicinchoninic acid (BCA)-proteinassay. | 2006-04 |
|
| Antiestrogens inhibit xenoestrogen-induced brain aromatase activity but do not prevent xenoestrogen-induced feminization in Japanese medaka (Oryzias latipes). | 2006-04 |
|
| Concurrent response to challenge infection with Cryptosporidium parvum in immunosuppressed C57BL/6N mice. | 2006-03 |
|
| Methylation of the insulin-like growth factor binding protein-3 gene and prognosis of epithelial ovarian cancer. | 2006-02-01 |
|
| Fetal intestinal fibroblasts respond to insulin-like growth factor (IGF)-II better than adult intestinal fibroblasts. | 2006-01-27 |
|
| Stable low-level expression of p21WAF1/CIP1 in A549 human bronchogenic carcinoma cell line-derived clones down-regulates E2F1 mRNA and restores cell proliferation control. | 2006-01-10 |
|
| Perinatal environmental tobacco smoke exposure in rhesus monkeys: critical periods and regional selectivity for effects on brain cell development and lipid peroxidation. | 2006-01 |
|
| Therapeutic impact of the ethyl acetate extract of Tripterygium wilfordii Hook F on nephritis in NZB/W F1 mice. | 2006 |
|
| Neogenin expression may be inversely correlated to the tumorigenicity of human breast cancer. | 2005-12-03 |
|
| Antitumor activity of TRAIL recombinant adenovirus in human malignant glioma cells. | 2005-12 |
|
| A novel endogenous inhibitor of the secreted streptococcal NAD-glycohydrolase. | 2005-12 |
|
| Smoking, oxidative stress and inflammation: impact on resting energy expenditure in diabetic nephropathy. | 2005-11-22 |
|
| Heat shock protein and heat shock factor 1 expression and localization in vaccinia virus infected human monocyte derived macrophages. | 2005-10-24 |
|
| The subcellular distribution of myeloid-related protein 8 (MRP8) and MRP14 in human neutrophils. | 2005-09-28 |
|
| Endothelial apoptotic activity of angiocidin is dependent on its polyubiquitin binding activity. | 2005-09-19 |
|
| Inhibition of dynamin-dependent endocytosis increases shedding of the amyloid precursor protein ectodomain and reduces generation of amyloid beta protein. | 2005-08-11 |
|
| Epigallocatechin-3-gallate suppresses galactose-alpha1,4-galactose-1beta,4-glucose ceramide expression in TNF-alpha stimulated human intestinal epithelial cells through inhibition of MAPKs and NF-kappaB. | 2005-08 |
|
| PEGylated interferon-alpha2b: a branched 40K polyethylene glycol derivative. | 2005-08 |
|
| Protein adsorption patterns on poloxamer- and poloxamine-stabilized solid lipid nanoparticles (SLN). | 2005-08 |
|
| Correction of anaemia through the use of darbepoetin alfa improves chemotherapeutic outcome in a murine model of Lewis lung carcinoma. | 2005-07-25 |
|
| Variation in transcriptional regulation of cyclin dependent kinase inhibitor p21waf1/cip1 among human bronchogenic carcinomas. | 2005-07-13 |
|
| A novel Geobacteraceae-specific outer membrane protein J (OmpJ) is essential for electron transport to Fe(III) and Mn(IV) oxides in Geobacter sulfurreducens. | 2005-07-06 |
|
| Decreased tear lipocalin concentration in patients with meibomian gland dysfunction. | 2005-07 |
|
| Zinc-finger domains of the transcriptional repressor KLF15 bind multiple sites in rhodopsin and IRBP promoters including the CRS-1 and G-rich repressor elements. | 2005-06-17 |
|
| The effect of simvastatin on the proliferation and differentiation of human bone marrow stromal cells. | 2005-06 |
|
| Research upregulation of CD23 (FcepsilonRII) expression in human airway smooth muscle cells (huASMC) in response to IL-4, GM-CSF, and IL-4/GM-CSF. | 2005-05-20 |
|
| Determination of the number-average degree of polymerization of cellodextrins and cellulose with application to enzymatic hydrolysis. | 2005-05-10 |
|
| Substance P levels and neutral endopeptidase activity in acute burn wounds and hypertrophic scar. | 2005-04 |
|
| Casodex treatment induces hypoxia-related gene expression in the LNCaP prostate cancer progression model. | 2005-03-24 |
|
| The mannose receptor is expressed by subsets of APC in non-lymphoid organs. | 2005-02-08 |
|
| Formulation and process parameters affecting protein encapsulation into PLGA microspheres during ethyl acetate-based microencapsulation process. | 2005-02 |
|
| Occupational asthma and rhinitis induced by a herbal medicine, Wonji (Polygala tenuifolia). | 2005-02 |
|
| A peptide corresponding to the neuropilin-1-binding site on VEGF(165) induces apoptosis of neuropilin-1-expressing breast tumour cells. | 2005-01-31 |
|
| Iron homeostasis in neuronal cells: a role for IREG1. | 2005-01-24 |
|
| Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture. | 2005 |
|
| Elevated levels of beta-endorphin in temporomandibular joint synovial lavage fluid of patients with closed lock. | 2005 |
|
| Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo. | 2005 |
|
| Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis. | 2005 |
|
| Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants. | 2005 |
|
| The "Transport Specificity Ratio": a structure-function tool to search the protein fold for loci that control transition state stability in membrane transport catalysis. | 2004-11-17 |
|
| Assessment of in vitro bioactivity of hyaluronic acid and sulfated hyaluronic acid functionalized electroactive polymer. | 2004-11-09 |
|
| Effect of roasting history and buffer composition on peanut protein extraction efficiency. | 2004-11 |
|
| Developmental context determines latency of MYC-induced tumorigenesis. | 2004-11 |
|
| Cyclic guanosine monophosphate role in human carcinoma pathogenesis. | 2004-10 |
|
| Activation of Erk and JNK MAPK pathways by acute swim stress in rat brain regions. | 2004-09-20 |
|
| Proinflammatory role of inducible nitric oxide synthase in acute hyperoxic lung injury. | 2004-09-15 |
|
| A rapid solid-phase fluorescence-based protein assay for quantitation of protein electrophoresis samples containing detergents, chaotropes, dyes, and reducing agents. | 2004-08 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:01:58 GMT 2025
by
admin
on
Mon Mar 31 19:01:58 GMT 2025
|
| Record UNII |
CX56TX9Y1I
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| Record Status |
Validated (UNII)
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| Record Version |
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BICINCHONINIC ACID
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CX56TX9Y1I
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214-990-9
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DTXSID8061638
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133815
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71068
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1245-13-2
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