U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 04:41:00 GMT 2023
Edited
by admin
on Sat Dec 16 04:41:00 GMT 2023
Protein Type ENZYME
Protein Sub Type CYTOCHROME P450
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
CWT22I5484
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CYTOCHROME P450 19A1
Common Name English
CYAR
Common Name English
CYP19
Common Name English
CYP19A1
Common Name English
ARO1
Common Name English
AROMATASE
Common Name English
CYTOCHROME P 450 19A1
Common Name English
HUMAN CYTOCHROME P450 19A1
Common Name English
Code System Code Type Description
UNIPROT
P11511
Created by admin on Sat Dec 16 04:41:01 GMT 2023 , Edited by admin on Sat Dec 16 04:41:01 GMT 2023
PRIMARY
FDA UNII
CWT22I5484
Created by admin on Sat Dec 16 04:41:01 GMT 2023 , Edited by admin on Sat Dec 16 04:41:01 GMT 2023
PRIMARY
CAS
9039-48-9
Created by admin on Sat Dec 16 04:41:01 GMT 2023 , Edited by admin on Sat Dec 16 04:41:01 GMT 2023
PRIMARY
Related Record Type Details
TISSUE EXPRESSION -> PARENT
INHIBITOR -> TARGET
Competitive inhibitor of the aromatase enzyme system; it inhibits the conversion of androgens to estrogens. Inhibits the aromatase enzyme by competitively binding to the heme of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues.
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR->OFF-TARGET
IC50
INHIBITOR -> TARGET
STIMULATOR->TARGET
INHIBITOR -> TARGET
SUBSTRATE -> METABOLIC ENZYME
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL