TRYPTOQUIVALINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C29H30N4O7
Molecular Weight	546.5711
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)[C@H](OC(C)=O)C1=NC2=CC=CC=C2C(=O)N1[C@@H]3C[C@@]4(OC3=O)[C@@H]5N(O)C(C)(C)C(=O)N5C6=C4C=CC=C6

InChI

InChIKey=CYNVLFGDEQQUPE-LDWWEUSWSA-N

InChI=1S/C29H30N4O7/c1-15(2)22(39-16(3)34)23-30-19-12-8-6-10-17(19)24(35)31(23)21-14-29(40-25(21)36)18-11-7-9-13-20(18)32-26(29)33(38)28(4,5)27(32)37/h6-13,15,21-22,26,38H,14H2,1-5H3/t21-,22+,26+,29+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C29H30N4O7
Molecular Weight	546.5711
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Assessment of ABCG2-mediated transport of xenobiotics across the blood-milk barrier of dairy animals using a new MDCKII in vitro model.	2013-09	23652544
Acyclovir is a substrate for the human breast cancer resistance protein (BCRP/ABCG2): implications for renal tubular transport and acyclovir-induced nephrotoxicity.	2011-09	21859328
Role of P-glycoprotein and breast cancer resistance protein-1 in the brain penetration and brain pharmacodynamic activity of the novel phosphatidylinositol 3-kinase inhibitor GDC-0941.	2010-09	20522663
Chrysin blocks topotecan-induced apoptosis in Caco-2 cells in spite of inhibition of ABC-transporters.	2010-08-15	20457140
Culture period-dependent change of function and expression of ATP-binding cassette transporters in Caco-2 cells.	2009-09	19505989
In vitro and in vivo interaction of moxidectin with BCRP/ABCG2.	2009-06-15	19428349
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.	2008-10-01	18829547
Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides.	2005-06	15749994
Expression and function of ABCB1 and ABCG2 in human placental tissue.	2005-04	15640379

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:54:56 GMT 2025` Edited by `admin` on `Mon Mar 31 19:54:56 GMT 2025`
Record UNII	CW5S8OP3VO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRYPTOQUIVALINE

Common Name

English

FUMITREMORGIN C

Preferred Name

English

SPIRO(FURAN-2(5H),9'-(9H)IMIDAZO(1,2-A)INDOLE)-3',5(2'H)-DIONE, 4-(2-(1-(ACETYLOXY)-2-METHYLPROPYL)-4-OXO-3(4H)-QUINAZOLINYL)-1',3,4,9'A-TETRAHYDRO-1'-HYDROXY-2',2'-DIMETHYL-, (9'S-(9'.ALPHA.(4S*(R*)),9'A.BETA.))-

Common Name

English

SPIRO(FURAN-2(5H),9'-(9H)IMIDAZO(1,2-A)INDOLE)-3',5(2'H)-DIONE, 4-(2-((1S)-1-(ACETYLOXY)-2-METHYLPROPYL)-4-OXO-3(4H)-QUINAZOLINYL)-1',3,4,9'A-TETRAHYDRO-1'-HYDROXY-2',2'-DIMETHYL-, (2S,4R,9'AS)-

Common Name

English

TRYPTOQUIVALINE C

Common Name

English

TRYPTOQUIVALINE A

Common Name

English

Code System Code Type Description

FDA UNII

CW5S8OP3VO