TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6

Approval Year

Substance Class	Protein
Protein Type	REGULATOR PROTEIN
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	CW4TQ5MST7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6

Common Name

English

PTPN6 EXPRESSED PROTEIN

Common Name

English

PTP-1C

Common Name

English

PROTEIN-TYROSINE PHOSPHATASE 1C

Common Name

English

PROTEIN-TYROSINE PHOSPHATASE SHP-1

Common Name

English

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Code System

Code

Type

Description

FDA UNII

CW4TQ5MST7

PRIMARY

UNIPROT

P29350

PRIMARY

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Subunit 0

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Related Record

Type

Details


					OT4AQX5MLU

SC-43

AGONIST -> TARGET

Comments:

Used a SHP-1 agonist SC-43 to dephosphorylate STAT3 thereby suppressing oncogenic STAT3 signaling and tested it in combination with docetaxel in TNBC cells

Interaction Type:

IN-VITRO

Amount:

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 67600 Da (average)

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