U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 18:04:16 GMT 2023
Edited
by admin
on Sat Dec 16 18:04:16 GMT 2023
Protein Type REGULATOR PROTEIN
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
CW4TQ5MST7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6
Common Name English
PTPN6 EXPRESSED PROTEIN
Common Name English
PTP-1C
Common Name English
PROTEIN-TYROSINE PHOSPHATASE 1C
Common Name English
PROTEIN-TYROSINE PHOSPHATASE SHP-1
Common Name English
HEMATOPOIETIC CELL PROTEIN-TYROSINE PHOSPHATASE
Common Name English
SH-PTP1
Common Name English
Code System Code Type Description
FDA UNII
CW4TQ5MST7
Created by admin on Sat Dec 16 18:04:16 GMT 2023 , Edited by admin on Sat Dec 16 18:04:16 GMT 2023
PRIMARY
UNIPROT
P29350
Created by admin on Sat Dec 16 18:04:16 GMT 2023 , Edited by admin on Sat Dec 16 18:04:16 GMT 2023
PRIMARY
Related Record Type Details
AGONIST -> TARGET
Used a SHP-​1 agonist SC-​43 to dephosphorylate STAT3 thereby suppressing oncogenic STAT3 signaling and tested it in combination with docetaxel in TNBC cells
IN-VITRO
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL